Pot1b Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pot1b
protection of telomeres 1B
MGI:1920086

12 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pot1b^tm1.1Schg/Pot1b^tm1.1Schg involves: 129/Sv * 129S6/SvEvTac * C57BL/6 * SJL	abnormal nail morphology	J:144553
	decreased body weight	J:144553
	decreased male germ cell number	J:144553
	hyperpigmentation	J:144553
	small testis	J:144553
Pot1b^tm1.1Schg/Pot1b^tm1.1Schg involves: 129S6/SvEvTac * C57BL/6	abnormal crypts of Lieberkuhn morphology	J:144553
	abnormal seminiferous tubule morphology	J:144553
	abnormal spermatogenesis	J:144553
	decreased body size	J:144553
	increased male germ cell apoptosis	J:144553
	reduced male fertility	J:144553
	small testis	J:144553
Pot1b^tm1Tdl/Pot1b^tm1Tdl involves: 129P2/OlaHsd * C57BL/6J	no abnormal phenotype detected	J:112185

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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