Auts2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Auts2
autism susceptibility candidate 2
MGI:1919847

28 phenotypes from 5 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Auts2^{em1(IMPC)Wtsi}/Auts2⁺ C57BL/6N-Auts2^{em1(IMPC)Wtsi}/Wtsi	decreased body length	J:211773
	increased lean body mass	J:211773
Auts2^{em1(IMPC)Wtsi}/Auts2^{em1(IMPC)Wtsi} C57BL/6N-Auts2^{em1(IMPC)Wtsi}/Wtsi	abnormal ductus venosus valve morphology	J:239583
	abnormal hypoglossal nerve topology	J:239583
	abnormal inferior vena cava morphology	J:239583
	abnormal interatrial septum morphology	J:239583
	abnormal Mullerian duct topology	J:239583
	absent segment of posterior cerebral artery	J:239583
	biliary cyst	J:239583
	embryo tumor	J:239583
	increased hemangioma incidence	J:239583
	preweaning lethality, complete penetrance	J:211773
Auts2^tm1.1Dare/Auts2⁺ Tg(Nes-cre)1Kln/0 involves: C57BL/6 * SJL	decreased body length	J:217675
	decreased vocalization	J:217675
Auts2^tm1.1Dare/Auts2^tm1.1Dare Tg(Nes-cre)1Kln/0 involves: C57BL/6 * SJL	decreased body length	J:217675
	decreased food intake	J:217675
	decreased vocalization	J:217675
	impaired righting response	J:217675
	positive geotaxis	J:217675
Auts2^tm1.1Mhos/Auts2^tm1.1Mhos involves: C57BL/6 * C57BL/6N	abnormal axon extension	J:243531
	abnormal neuronal migration	J:243531
Auts2^tm1.2Mhos/Auts2⁺ involves: C57BL/6 * C57BL/6N	abnormal collateral sprouting	J:243531
Auts2^tm1.2Mhos/Auts2⁺ involves: C57BL/6 * C57BL/6N	abnormal neuronal migration	J:243531
Auts2^tm1.2Mhos/Auts2^tm1.2Mhos involves: C57BL/6 * C57BL/6N	abnormal axon extension	J:243531
	abnormal collateral sprouting	J:243531
	abnormal neuronal migration	J:243531
	neonatal lethality, complete penetrance	J:243531
Auts2^tm1Mhos/Auts2⁺ C57BL/6N-Auts2^tm1Mhos	abnormal habituation to a new environment	J:261355
	abnormal neuronal migration	J:243531
	normal behavior/neurological phenotype	J:261355
	decreased anxiety-related response	J:261355
	decreased body weight	J:261355
	decreased exploration in new environment	J:261355
	impaired cued conditioning behavior	J:261355
	impaired long-term object recognition memory	J:261355
	increased startle reflex	J:261355
Auts2^tm1Mhos/Auts2^tm1Mhos C57BL/6N-Auts2^tm1Mhos	abnormal neuronal migration	J:243531
Auts2^tm1Mhos/Auts2^tm1Mhos C57BL/6N-Auts2^tm1Mhos	neonatal lethality, complete penetrance	J:243531

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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