Mcm9 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mcm9
minichromosome maintenance 9 homologous recombination repair factor
MGI:1918817

30 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mcm9^{Gt(AW0655)Wtsi}/Mcm9^{Gt(AW0655)Wtsi} involves: 129P2/OlaHsd * C3HeB/FeJ	abnormal seminiferous tubule morphology	J:177420
	abnormal spermatogonia morphology	J:177420
	arrest of male meiosis	J:177420
	decreased male germ cell number	J:177420
	female infertility	J:177420
	increased adenoma incidence	J:177420
	increased hepatocellular carcinoma incidence	J:177420
	increased ovary tumor incidence	J:177420
	increased tumor incidence	J:177420
	normal mortality/aging	J:177420
	oligozoospermia	J:177420
	ovary hyperplasia	J:177420
	premature ovarian failure	J:177420
	small testis	J:177420
Mcm9^{Gt(AW0655)Wtsi}/Mcm9^Gt(XG743)Byg involves: 129P2/OlaHsd * C3HeB/FeJ	abnormal seminiferous tubule morphology	J:177420
	abnormal spermatogonia morphology	J:177420
	arrest of male meiosis	J:177420
	decreased male germ cell number	J:177420
	increased hepatocellular carcinoma incidence	J:177420
	increased ovary tumor incidence	J:177420
	increased tumor incidence	J:177420
	normal mortality/aging	J:177420
	oligozoospermia	J:177420
	small testis	J:177420
Mcm9^Gt(XG743)Byg/Mcm9^Gt(XG743)Byg involves: 129P2/OlaHsd * C3HeB/FeJ	abnormal cell cycle	J:177420
	abnormal definitive hematopoiesis	J:177420
	abnormal female germ cell morphology	J:177420
	abnormal ovarian follicle number	J:177420
	abnormal seminiferous tubule morphology	J:177420
	abnormal spermatogonia morphology	J:177420
	arrest of male meiosis	J:177420
	decreased male germ cell number	J:177420
	decreased oocyte number	J:177420
	decreased primordial germ cell number	J:177420
	decreased primordial ovarian follicle number	J:177420
	early cellular replicative senescence	J:177420
	increased hepatocellular carcinoma incidence	J:177420
	increased ovary tumor incidence	J:177420
	increased tumor incidence	J:177420
	normal mortality/aging	J:177420
	oligozoospermia	J:177420
	normal reproductive system phenotype	J:177420
	small testis	J:177420
	spontaneous chromosome breakage	J:177420
Mcm9^tm1.1Geno/Mcm9^tm1.1Geno involves: 129S2/SvPas * C57BL/6J	abnormal cell nucleus morphology	J:187623
	abnormal DNA replication	J:187623
	abnormal male germ cell apoptosis	J:187623
	abnormal seminiferous tubule morphology	J:187623
	decreased fibroblast proliferation	J:187623
	female infertility	J:187623
	increased cellular sensitivity to gamma-irradiation	J:187623
	oligozoospermia	J:187623
	polyploidy	J:187623
	normal reproductive system phenotype	J:187623
	spontaneous chromosome breakage	J:187623

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