Ace2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ace2
angiotensin converting enzyme 2
MGI:1917258

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ace2^em2(ACE2)Gpt/Y C57BL/6JGpt-Ace2^em2(ACE2)Gpt/Gpt	increased susceptibility to Coronaviridae infection	J:302150
	increased susceptibility to weight loss	J:302150
	lung inflammation	J:302150
Ace2^tm1Pngr/Y Pik3cg^tm1Pngr/Pik3cg^tm1Pngr involves: 129P2/OlaHsd * C57BL/6	increased cardiac muscle contractility	J:124548
Ace^tm1Unc/Ace^tm1Unc Ace2^tm1Pngr/Y involves: 129P2/OlaHsd	abnormal kidney morphology	J:77232
	decreased angiotensin II level	J:100334
	decreased circulating angiotensin II level	J:100334
	decreased susceptibility to injury	J:100334
	hypotension	J:77232
Ace^tm1Unc/Ace^tm1Unc Ace2^tm1Pngr/Ace2^tm1Pngr involves: 129P2/OlaHsd	abnormal kidney morphology	J:77232
	decreased angiotensin II level	J:100334
	decreased circulating angiotensin II level	J:100334
	decreased susceptibility to injury	J:100334
	hypotension	J:77232

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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