Upf3a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Upf3a
UPF3 regulator of nonsense transcripts homolog A (yeast)
MGI:1914281

19 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(KRT5-cre/ERT2)2Ipc/0 Upf3a^tm1.1Wilk/Upf3a^tm1.1Wilk involves: 129 * 129S4/SvJaeSor * C57BL/6 * SJL	abnormal cell physiology	J:234504
Tg(Stra8-icre)1Reb/0 Upf3a^tm1.1Wilk/Upf3a⁺ involves: 129 * 129S4/SvJaeSor * C57BL/6 * FVB/NJ	abnormal spermatocyte morphology	J:234504
	decreased male germ cell number	J:234504
Upf3a^em1(IMPC)Mbp/Upf3a^em1(IMPC)Mbp C57BL/6NCrl-Upf3a^em1(IMPC)Mbp/Mmucd	abnormal eye morphology	J:211773
	abnormal testis morphology	J:211773
	decreased exploration in new environment	J:211773
	male infertility	J:211773
	small testis	J:211773
Upf3a^tm1.1Wilk/Upf3a^tm1.1Wilk Tg(Stra8-icre)1Reb/0 involves: 129 * 129S4/SvJaeSor * C57BL/6 * FVB/NJ	abnormal cell physiology	J:234504
	abnormal male meiosis	J:234504
	abnormal spermatid morphology	J:234504
	abnormal spermatocyte morphology	J:234504
	abnormal spermatogonia morphology	J:234504
	normal cellular phenotype	J:234504
	decreased male germ cell number	J:234504
	normal growth/size/body region phenotype	J:234504
	increased male germ cell apoptosis	J:234504
	oligozoospermia	J:234504
Upf3a^tm1.2Wilk/Upf3a⁺ involves: 129 * C57BL/6	normal mortality/aging	J:234504
Upf3a^tm1.2Wilk/Upf3a^tm1.2Wilk involves: 129 * C57BL/6	abnormal embryo morphology	J:234504
	embryonic lethality between implantation and somite formation	J:234504
	embryonic lethality, complete penetrance	J:234504

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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