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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Upf3a
UPF3 regulator of nonsense transcripts homolog A (yeast)
MGI:1914281
16 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Tg(KRT5-cre/ERT2)2Ipc/0
Upf3atm1.1Wilk/Upf3atm1.1Wilk
involves: 129 * 129S4/SvJaeSor * C57BL/6 * SJL
abnormal cell physiology J:234504
Tg(Stra8-icre)1Reb/0
Upf3atm1.1Wilk/Upf3a+
involves: 129 * 129S4/SvJaeSor * C57BL/6 * FVB/NJ
abnormal spermatocyte morphology J:234504
decreased male germ cell number J:234504
Tg(Stra8-icre)1Reb/0
Upf3atm1.1Wilk/Upf3atm1.1Wilk
involves: 129 * 129S4/SvJaeSor * C57BL/6 * FVB/NJ
abnormal cell physiology J:234504
abnormal male meiosis J:234504
abnormal spermatid morphology J:234504
abnormal spermatocyte morphology J:234504
abnormal spermatogonia morphology J:234504
normal cellular phenotype J:234504
decreased male germ cell number J:234504
normal growth/size/body region phenotype J:234504
increased male germ cell apoptosis J:234504
oligozoospermia J:234504
Upf3aem1(IMPC)Mbp/Upf3aem1(IMPC)Mbp
C57BL/6NCrl-Upf3aem1(IMPC)Mbp/Mmucd
decreased circulating alanine transaminase level J:211773
male infertility J:211773
Upf3atm1.2Wilk/Upf3a+
involves: 129 * C57BL/6
normal mortality/aging J:234504
Upf3atm1.2Wilk/Upf3atm1.2Wilk
involves: 129 * C57BL/6
abnormal embryo morphology J:234504
embryonic lethality between implantation and somite formation J:234504
embryonic lethality, complete penetrance J:234504

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory