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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sppl2a
signal peptide peptidase like 2A
MGI:1913802
11 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cd74tm1Liz/Cd74tm1Liz
Sppl2atm1Basc/Sppl2atm1Basc
B6.129-Sppl2atm1Basc Cd74tm1Liz 		decreased B cell number J:194664
decreased Peyer's patch number J:194664
normal immune system phenotype J:194664
Cd74tm1Liz/Cd74tm1Liz
Sppl2atm1Dgen/Sppl2atm1Dgen
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 		decreased follicular B cell number J:194595
normal immune system phenotype J:194595
Sppl2am1Anu/Sppl2am1Anu
Tg(Vav-BCL2)69Jad/?
involves: C57BL/6JAnu 		abnormal T cell number J:194663
decreased CD4-positive, alpha-beta T cell number J:194663
decreased double-negative T cell number J:194663
increased mature B cell number J:194663
increased plasmacytoid dendritic cell number J:194663
Sppl2atm1Basc/Sppl2atm1Basc
Sppl2bGt(Ayu21-T160)Imeg/Sppl2bGt(Ayu21-T160)Imeg
B6N.Cg-Sppl2atm1Basc Sppl2bGt(Ayu21-T160)Imeg 		abnormal mature B cell morphology J:213519
decreased B cell number J:213519
decreased immunoglobulin level J:213519
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory