Sln Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sln
sarcolipin
MGI:1913652

22 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sln^em1Cyh/Sln^em1Cyh Not Specified	normal growth/size/body region phenotype	J:284048
Sln^em1Cyh/Sln^em1Cyh Not Specified	normal mortality/aging	J:284048
Sln^tm1Peri/Sln^tm1Peri involves: Black Swiss * C57BL/6	normal cardiovascular system phenotype	J:127150
Sln^tm1Peri/Sln^tm1Peri involves: Black Swiss * C57BL/6	increased cardiac muscle contractility	J:127150
Sln^tm1Peri/Sln^tm1Peri involves: C57BL/6J	decreased body temperature	J:193427
	decreased food intake	J:193427
	decreased oxygen consumption	J:193427
	hepatic steatosis	J:193427
	impaired adaptive thermogenesis	J:193427
	impaired glucose tolerance	J:193427
	increased body fat mass	J:193427
	increased brown fat cell lipid droplet size	J:193427
	increased circulating cholesterol level	J:193427
	increased circulating glucose level	J:193427
	increased circulating triglyceride level	J:193427
	increased susceptibility to diet-induced obesity	J:193427
	increased susceptibility to induced morbidity/mortality	J:193427
	increased total fat pad weight	J:193427
	increased white fat cell lipid droplet size	J:193427
Tg(Myh6-Sln)26Peri/0 involves: C57BL/6	abnormal calcium ion homeostasis	J:108309
	abnormal cardiac muscle relaxation	J:108309
	decreased cardiac muscle contractility	J:108309

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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