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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Nek7
NIMA (never in mitosis gene a)-related expressed kinase 7
MGI:1890645
29 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Nek7Gt(AR1081)Wtsi/Nek7Gt(AR1081)Wtsi
involves: 129P2/OlaHsd
normal vision/eye phenotype J:180113
Nek7Gt(NPX451)Byg/Nek7Gt(NPX451)Byg
involves: 129P2/OlaHsd
normal vision/eye phenotype J:180113
Nek7M1Btlr/Nek7+
C57BL/6J-Nek7M1Btlr
abnormal macrophage physiology J:226677
decreased inflammatory response J:226677
decreased interleukin-1 beta secretion J:226677
decreased interleukin-18 secretion J:226677
normal hematopoietic system phenotype J:226677
normal immune system phenotype J:226677
Nek7M1Btlr/Nek7M1Btlr
C57BL/6J-Nek7M1Btlr
abnormal gait J:226677
abnormal macrophage physiology J:226677
decreased body weight J:226677
decreased inflammatory response J:226677
decreased interleukin-1 beta secretion J:226677
decreased interleukin-18 secretion J:226677
decreased susceptibility to experimental autoimmune encephalomyelitis J:226677
normal hematopoietic system phenotype J:226677
normal immune system phenotype J:226677
infertility J:226677
paresis J:226677
Nek7tm1b(EUCOMM)Hmgu/Nek7+
C57BL/6N-Nek7tm1b(EUCOMM)Hmgu/J
abnormal bone structure J:211773
decreased circulating glucose level J:211773
increased bone mineral content J:211773
increased bone mineral density J:211773
increased urine microalbumin level J:211773
Nek7tm1b(EUCOMM)Hmgu/Nek7tm1b(EUCOMM)Hmgu
C57BL/6N-Nek7tm1b(EUCOMM)Hmgu/J
preweaning lethality, complete penetrance J:211773
Nek7tm1Mot/Nek7tm1Mot
involves: 129S1/Sv * 129X1/SvJ
normal vision/eye phenotype J:180113
Nek7tm1Mot/Nek7tm1Mot
involves: 129S1/Sv * 129X1/SvJ * BALB/c * ICR
abnormal mitosis J:168166
aneuploidy J:168166
binucleate J:168166
chromosomal instability J:168166
decreased birth weight J:168166
embryonic lethality during organogenesis, incomplete penetrance J:168166
lethality throughout fetal growth and development, incomplete penetrance J:168166
perinatal lethality, incomplete penetrance J:168166
polyploidy J:168166
postnatal growth retardation J:168166
postnatal lethality, incomplete penetrance J:168166
preweaning lethality, complete penetrance J:168166

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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory