Panx1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Panx1
pannexin 1
MGI:1860055

14 phenotypes from 6 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Panx1^tm1.1Fama/Panx1^tm1.1Fama involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal neuron physiology	J:177671
	decreased susceptibility to pharmacologically induced seizures	J:177671
	normal hearing/vestibular/ear phenotype	J:178055
Panx1^tm1.1Vshe/Panx1^tm1.1Vshe B6.129-Panx1^tm1.1Vshe	abnormal response to injury	J:196355
	decreased neuron apoptosis	J:196355
	increased retina ganglion cell number	J:196355
Panx1^tm1.2Vmd/Panx1^tm1.2Vmd C57BL/6N-Panx1^tm1.2Vmd	abnormal T cell physiology	J:173213
Panx1^tm1.2Vmd/Panx1^tm1.2Vmd C57BL/6N-Panx1^tm1.2Vmd	normal immune system phenotype	J:173213
Panx1^{tm1a(KOMP)Wtsi}/Panx1^{tm1a(KOMP)Wtsi} involves: C57BL/6 * C57BL/6N	abnormal neuron physiology	J:177671
	decreased susceptibility to pharmacologically induced seizures	J:177671
Panx1^{tm1a(KOMP)Wtsi}/Panx1^{tm1a(KOMP)Wtsi} involves: C57BL/6N	abnormal cell physiology	J:175396
	abnormal respiratory system physiology	J:175396
Panx1^{tm1b(KOMP)Wtsi}/Panx1^{tm1b(KOMP)Wtsi} C57BL/6N-Panx1^{tm1b(KOMP)Wtsi}/Ucd	abnormal behavior	J:211773
	decreased circulating serum albumin level	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased thigmotaxis	J:211773
Panx1^tm1Vshe/Panx1^tm1Vshe Tg(Thy1-cre)1Vln/0 B6.Cg-Panx1^tm1Vshe Tg(Thy1-cre)1Vln	abnormal response to injury	J:196355
	decreased neuron apoptosis	J:196355
	increased retina ganglion cell number	J:196355

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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