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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Dnmt3l
DNA methyltransferase 3-like
MGI:1859287
26 phenotypes from 6 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Dnmt3lem1(IMPC)Bay/Dnmt3lem1(IMPC)Bay
C57BL/6N-Dnmt3lem1(IMPC)Bay/BayMmucd
female infertility J:211773
male infertility J:211773
Dnmt3ltm1b(EUCOMM)Hmgu/Dnmt3ltm1b(EUCOMM)Hmgu
C57BL/6N-Dnmt3ltm1b(EUCOMM)Hmgu/Ieg
increased bone mineral density J:211773
increased mean corpuscular hemoglobin J:211773
persistence of hyaloid vascular system J:211773
small testis J:211773
Dnmt3ltm1Bes/Dnmt3ltm1Bes
involves: 129S6/SvEvTac
abnormal chorion morphology J:73452
abnormal ectoplacental cone morphology J:73452
abnormal oogenesis J:73452
abnormal spermatogenesis J:128710
abnormal trophoblast layer morphology J:73452
abnormal visceral yolk sac endoderm morphology J:73452
azoospermia J:73452
decreased male germ cell number J:128710
exencephaly J:73452
failure of chorioallantoic fusion J:73452
female infertility J:73452
increased trophoblast giant cell number J:73452
infertility J:73452
male infertility J:73452
pericardial edema J:73452
prenatal lethality, complete penetrance J:73452
small testis J:73452
Dnmt3ltm1Enl/Dnmt3ltm1Enl
involves: 129S4/SvJae
abnormal chorion morphology J:75938
abnormal oogenesis J:75938
abnormal spermiogenesis J:75938
infertility J:75938
open neural tube J:75938
prenatal lethality, complete penetrance J:75938
small testis J:75938
Dnmt3ltm1Scot/Dnmt3ltm1Scot
C57BL/6-Dnmt3ltm1Scot
abnormal seminiferous tubule epithelium morphology J:97190
arrest of male meiosis J:97190
azoospermia J:97190
infertility J:97190
small gonad J:97190
Dnmt3ltm2Bes/Dnmt3ltm2Bes
involves: 129
no abnormal phenotype detected J:123743

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory