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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Nr2f1
nuclear receptor subfamily 2, group F, member 1
MGI:1352451
48 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Nr2f1tm1.1(KOMP)Mbp/Nr2f1+
C57BL/6N-Nr2f1tm1.1(KOMP)Mbp/J
abnormal auditory brainstem response J:211773
Nr2f1tm1.1(KOMP)Mbp/Nr2f1tm1.1(KOMP)Mbp
C57BL/6N-Nr2f1tm1.1(KOMP)Mbp/J
embryonic growth retardation J:211773
preweaning lethality, complete penetrance J:211773
Nr2f1tm1Mist/Nr2f1tm1Mist
involves: 129S2/SvPas * C57BL/6J
abnormal anterior commissure morphology J:114098
abnormal axon guidance J:114098
abnormal axon morphology J:114098
abnormal brain commissure morphology J:114098
abnormal cerebral cortex morphology J:114098
abnormal cingulate gyrus morphology J:114098
abnormal corpus callosum morphology J:114098
abnormal hippocampal commissure morphology J:114098
abnormal neuron morphology J:114098
perinatal lethality, complete penetrance J:114098
Nr2f1tm1Mjts/Nr2f1+
involves: 129S7/SvEvBrd
abnormal dorsal striatum morphology J:286647
abnormal long-term depression J:286647
normal behavior/neurological phenotype J:286647
decreased body weight J:286647
decreased grip strength J:286647
decreased hippocampus volume J:286647
decreased startle reflex J:286647
hypotonia J:286647
impaired hearing J:286647
impaired righting response J:286647
impaired synaptic plasticity J:286647
increased neocortex volume J:286647
increased or absent threshold for auditory brainstem response J:286647
reduced long-term potentiation J:286647
slow extinction of fear memory J:286647
normal vision/eye phenotype J:286647
Nr2f1tm1Mjts/Nr2f1tm1Mjts
involves: 129S7/SvEvBrd
abnormal cerebral cortex morphology J:59182, J:71195
abnormal cochlear hair cell development J:112461
abnormal cochlear sensory epithelium morphology J:112461
abnormal hearing physiology J:59182
abnormal organ of Corti supporting cell differentiation J:112461
abnormal orientation of inner hair cell stereociliary bundles J:112461
abnormal orientation of outer hair cell stereociliary bundles J:112461
absent barrels in primary somatosensory cortex J:59182
increased cochlear hair cell number J:112461
increased cochlear inner hair cell number J:112461
increased cochlear outer hair cell number J:112461
increased Deiters cell number J:112461
short scala media J:112461
Nr2f1tm1Mjts/Nr2f1tm1Mjts
involves: 129S7/SvEvBrd * C57BL/6
abnormal axon guidance J:42259
abnormal glossopharyngeal ganglion morphology J:42259
neonatal lethality, incomplete penetrance J:42259
normal nervous system phenotype J:42259
no swallowing reflex J:42259
Nr2f1tm2.1Mist/Nr2f1tm2.1Mist
involves: 129S2/SvPas * C57BL/6J
no abnormal phenotype detected J:127387
Nr2f1tm2.1Mist/Nr2f1tm2.1Mist
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J
abnormal barrel cortex morphology J:127387
abnormal cerebral cortex morphology J:127387
abnormal primary somatosensory cortex morphology J:127387
normal nervous system phenotype J:127387
Nr2f1tm2.1Mjts/Nr2f1tm2.1Mjts
Tg(rx3-icre)1Mjam/0
involves: 129
normal vision/eye phenotype J:157924

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory