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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Abcg5
ATP binding cassette subfamily G member 5
MGI:1351659
23 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Abcb4tm1Bor/Abcb4tm1Bor
Tg(ABCG5/ABCG8)14-2Hobb/0
involves: 129P2/OlaHsd * C57BL/6J * FVB/N * SJL
abnormal bile composition J:100491
abnormal feces composition J:100491
decreased intestinal cholesterol absorption J:100491
normal homeostasis/metabolism phenotype J:100491
increased circulating alanine transaminase level J:100491
increased circulating aspartate transaminase level J:100491
Abcg5tm1.1Hobb/Abcg5tm1.1Hobb
Abcg8tm1.1Hobb/Abcg8tm1.1Hobb
Speer6-ps1Tg(Alb-cre)21Mgn/?
involves: C57BL/6 * DBA * SJL
abnormal cellular cholesterol metabolism J:215443
abnormal feces composition J:215443
abnormal intestinal cholesterol absorption J:215443
abnormal phytosterol level J:215443
decreased cholesterol efflux J:215443
decreased circulating cholesterol level J:215443
decreased phytosterol level J:215443
increased cholesterol level J:215443
increased circulating phytosterol level J:215443
Abcg5tm1.1Hobb/Abcg5tm1.1Hobb
Abcg8tm1.1Hobb/Abcg8tm1.1Hobb
Tg(CAG-cre/Esr1*)5Amc/?
involves: C57BL/6 * CBA * SJL
abnormal cellular cholesterol metabolism J:215443
abnormal feces composition J:215443
abnormal phytosterol level J:215443
decreased cholesterol efflux J:215443
decreased cholesterol level J:215443
decreased circulating cholesterol level J:215443
decreased phytosterol level J:215443
increased circulating phytosterol level J:215443
increased intestinal phytosterol absorption J:215443
increased phytosterol level J:215443
Abcg5tm1.1Hobb/Abcg5tm1.1Hobb
Abcg8tm1.1Hobb/Abcg8tm1.1Hobb
Tg(Vil1-cre)997Gum/?
involves: C57BL/6 * SJL
abnormal cellular cholesterol metabolism J:215443
abnormal feces composition J:215443
decreased cholesterol efflux J:215443
increased circulating phytosterol level J:215443
increased intestinal phytosterol absorption J:215443
increased phytosterol level J:215443
Tg(ABCG5/ABCG8)14-2Hobb/0
involves: C57BL/6J * SJL
abnormal bile composition J:78963, J:100491
abnormal cholesterol homeostasis J:78963
abnormal circulating phytosterol level J:78963, J:100491
abnormal feces composition J:78963, J:100491
abnormal intestinal absorption J:100491
decreased circulating cholesterol level J:78963
decreased circulating HDL cholesterol level J:78963
decreased intestinal cholesterol absorption J:78963, J:100491
decreased susceptibility to hepatic steatosis J:78963
increased cholesterol level J:78963
steatorrhea J:78963

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory