Bcap31 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bcap31
B cell receptor associated protein 31
MGI:1350933

20 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Bcap31^tm1.1Bwang/Bcap31^tm1.1Bwang Lyz2^tm1(cre)Ifo/Lyz2⁺ involves: 129P2/OlaHsd * C57BL/6	abnormal enzyme/coenzyme level	J:292505
	abnormal spatial reference memory	J:292505
	normal behavior/neurological phenotype	J:292505
	decreased neuron number	J:292505
	increased inflammatory response	J:292505
	increased interleukin-1 beta secretion	J:292505
	increased microglial cell activation	J:292505
	increased tumor necrosis factor secretion	J:292505
Bcap31^tm1.1Bwang/Bcap31^tm1.1Bwang Tg(Lck-cre)548Jxm/0 involves: C57BL/6 * CBA	abnormal T cell activation	J:274469
	decreased CD8-positive, naive alpha-beta T cell number	J:274469
	decreased interferon-gamma secretion	J:274469
	decreased interleukin-2 secretion	J:274469
	decreased single-positive T cell number	J:274469
	decreased T cell proliferation	J:274469
	decreased thymocyte number	J:274469
	decreased thymus weight	J:274469
	increased effector memory T-helper cell number	J:274469
	increased thymocyte apoptosis	J:274469
	small thymus	J:274469
	thymus hypoplasia	J:274469

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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