Ncor1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ncor1
nuclear receptor co-repressor 1
MGI:1349717

50 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ncor1^tm1.1Anh/Ncor1^tm1.1Anh involves: 129S4/SvJae * C57BL/6J	abnormal response/metabolism to endogenous compounds	J:213990
	abnormal thyroxine level	J:213990
	normal behavior/neurological phenotype	J:213990
	decreased activity of thyroid gland	J:213990
	decreased body weight	J:213990
	decreased circulating thyroxine level	J:213990
	decreased circulating triiodothyronine level	J:213990
	decreased heart rate	J:213990
	decreased total body fat amount	J:213990
	normal endocrine/exocrine gland phenotype	J:213990
	normal homeostasis/metabolism phenotype	J:213990
	increased energy expenditure	J:213990
	increased heart left ventricle weight	J:213990
	increased heart weight	J:213990
	increased oxygen consumption	J:213990
	normal mortality/aging	J:213990
Ncor1^tm1.1Ics/Ncor1^tm1.1Ics involves: 129 * C57BL/6J	decreased liver glycogen level	J:206152
Ncor1^tm1.1Ics/Ncor1^tm1.1Ics involves: 129 * C57BL/6J	hepatic steatosis	J:206152
Ncor1^tm1.1Ics/Ncor1^tm1.1Ics Tg(ACTA1-cre)79Jme/0 involves: 129 * C57BL/6 * C57BL/6J * SJL	abnormal aerobic fitness	J:178827
	abnormal gas homeostasis	J:178827
	abnormal gastrocnemius morphology	J:178827
	abnormal muscle physiology	J:178827
	abnormal quadriceps morphology	J:178827
	abnormal skeletal muscle fiber mitochondrial morphology	J:178827
	abnormal skeletal muscle morphology	J:178827
	abnormal soleus morphology	J:178827
	decreased circulating cholesterol level	J:178827
	decreased circulating HDL cholesterol level	J:178827
	decreased circulating LDL cholesterol level	J:178827
	decreased respiratory quotient	J:178827
	decreased susceptibility to induced hypothermia	J:178827
	enhanced exercise endurance	J:178827
	increased locomotor activity	J:178827
	increased oxygen consumption	J:178827
	increased skeletal muscle fiber diameter	J:178827
Ncor1^tm1Anh/Ncor1^tm1Anh Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * DBA	decreased circulating LDL cholesterol level	J:142045
	decreased circulating thyroxine level	J:142045
Ncor1^tm1Rsd/Ncor1^tm1Rsd involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal erythropoiesis	J:65417
	abnormal hematocrit	J:65417
	abnormal hepatocyte morphology	J:65417
	anemia	J:65417
	arrested T cell differentiation	J:65417
	decreased embryo size	J:65417
	decreased erythrocyte cell number	J:65417
	decreased hematocrit	J:65417
	dilated third ventricle	J:65417
	edema	J:65417
	increased nucleated erythrocyte cell number	J:65417
	lethality throughout fetal growth and development, complete penetrance	J:65417
	pallor	J:65417
	small liver	J:65417
	small thalamus	J:65417
	small thymus	J:65417

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