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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Igbp1
immunoglobulin (CD79A) binding protein 1
MGI:1346500
16 phenotypes from 2 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cd19tm1(cre)Cgn/Cd19+
Igbp1tm1Imku/Y
involves: 129P2/OlaHsd 		abnormal B cell physiology J:74619
abnormal somatic hypermutation frequency J:74619
abnormal spleen germinal center morphology J:74619
decreased B cell number J:74619
decreased B cell proliferation J:74619
decreased follicular B cell number J:74619
decreased immunoglobulin level J:74619
decreased pre-B cell number J:74619
Igbp1tm1Cbt/Igbp1+
Tg(Lck-cre)1Cwi/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 		decreased thymocyte number J:93221
Igbp1tm1Cbt/Y
Tg(Lck-cre)1Cwi/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 		decreased thymocyte number J:93221
Igbp1tm1Imku/Y
Tg(Igbp1b-cre)1Imku/0
B6.Cg-Igbp1tm1Imku Tg(Igbp1b-cre)1Imku 		abnormal cued conditioning behavior J:107484
abnormal spatial learning J:107484
normal nervous system phenotype J:107484
Igbp1tm1Imku/Y
Tg(Lck-cre)I57Jxm/?
involves: 129P2/OlaHsd * ICR 		abnormal thymus cortex morphology J:84395
abnormal thymus corticomedullary boundary morphology J:84395
decreased double-negative T cell number J:84395
decreased T cell number J:84395
decreased thymocyte number J:84395
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory