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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Dgat1
diacylglycerol O-acyltransferase 1
MGI:1333825
38 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Dgat1tm1Far/Dgat1tm1Far
B6J.129S4-Dgat1tm1Far
abnormal branching of the mammary ductal tree J:128259
abnormal mammary gland alveolus morphology J:128259
abnormal mammary gland development J:128259
abnormal mammary gland epithelium morphology J:128259
abnormal mammary gland growth during lactation J:128259
abnormal milk composition J:128259
decreased mammary fat pad weight J:128259
decreased mammary gland epithelial cell proliferation J:128259
impaired mammary gland growth during pregnancy J:128259
lactation failure J:128259
Dgat1tm1Far/Dgat1tm1Far
involves: 129S4/SvJae * C57BL/6J
abnormal coat/ hair morphology J:147611
abnormal epidermal layer morphology J:147611
abnormal hair cycle J:147611
abnormal hair cycle anagen phase J:147611
abnormal hair shedding J:147611
abnormal skin condition J:147611
abnormal vitamin A level J:147611
alopecia J:147611
decreased body weight J:111346
decreased circulating glucose level J:111346
decreased circulating leptin level J:111346
decreased liver cholesterol level J:111346
decreased liver triglyceride level J:111346
decreased percent body fat/body weight J:111346
decreased susceptibility to diet-induced hepatic steatosis J:111346
decreased susceptibility to diet-induced obesity J:61885
epidermal hyperplasia J:147611
hyperactivity J:61885
improved glucose tolerance J:111346
increased insulin sensitivity J:61885
increased oxygen consumption J:111346
lactation failure J:61885
reddish skin J:147611
scaly skin J:147611
skin lesions J:147611
sparse hair J:147611
thick epidermis J:147611
Dgat1tm1Ryyo/Dgat1tm1Ryyo
involves: C57BL/6
abnormal digestion J:155626
decreased circulating triglyceride level J:155626
Dgat1tm2Far/Dgat1tm2Far
Tg(KRT14-cre)1Amc/?
involves: 129S4/SvJae * C57BL/6 * CBA
alopecia J:147611

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory