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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lmbr1l
limb region 1 like
MGI:1289247
34 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Lmbr1lem1Btlr/Lmbr1lem1Btlr
C57BL/6J-Lmbr1lem1Btlr
abnormal alpha-beta T cell morphology J:274568
abnormal B cell differentiation J:274568
abnormal bone marrow cell morphology/development J:274568
abnormal cytotoxic T cell physiology J:274568
abnormal lymphocyte morphology J:274568
decreased CD4-positive, alpha-beta T cell number J:274568
decreased common lymphocyte progenitor cell number J:274568
decreased IgD level J:274568
decreased IgG level J:274568
decreased IgM level J:274568
decreased leukocyte cell number J:274568
decreased lymphocyte cell number J:274568
decreased monocyte cell number J:274568
decreased T cell number J:274568
impaired humoral immune response J:274568
impaired natural killer cell mediated cytotoxicity J:274568
increased hematopoietic cell number J:274568
increased IgM level J:274568
Lmbr1lm1Btlr/Lmbr1lm1Btlr
C57BL/6J-Lmbr1lm1Btlr
abnormal CD4-positive T cell differentiation J:274568
abnormal CD8-positive, alpha-beta T cell differentiation J:274568
abnormal cytotoxic T cell physiology J:274568
abnormal T cell differentiation J:274568
decreased CD4-positive, alpha-beta T cell number J:274568
decreased CD8-positive, alpha-beta T cell number J:274568
decreased CD8-positive, naive alpha-beta T cell number J:274568
decreased dendritic cell number J:274568
decreased IgE level J:274568
decreased IgG level J:274568
decreased IgM level J:274568
decreased NK cell number J:274568
decreased NK T cell number J:274568
decreased T cell number J:274568
impaired humoral immune response J:274568
impaired natural killer cell mediated cytotoxicity J:274568
increased B-1 B cell number J:274568
increased central memory CD8 positive, alpha-beta T cell number J:274568
increased effector memory CD4-positive, alpha-beta T cell number J:274568
increased macrophage cell number J:274568
increased neutrophil cell number J:274568
Lmbr1lm2Btlr/Lmbr1lm2Btlr
C57BL/6J-Lmbr1lm2Btlr
increased central memory CD4-positive, alpha-beta T cell number J:274857
Lmbr1ltm1Dgen/Lmbr1ltm1Dgen
involves: 129P2/OlaHsd * C57BL/6
no abnormal phenotype detected J:101679

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory