92 phenotypes from 7 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd19tm1(cre)Cgn/Cd19+ Ep300tm2Reck/Ep300+ involves: 129/Sv * 129P2/OlaHsd * C57BL/6	abnormal adaptive immunity	J:147840
	abnormal B cell differentiation	J:147840
	abnormal humoral immune response	J:147840
	abnormal renal glomerulus morphology	J:147840
	abnormal spleen marginal zone macrophage morphology	J:147840
	abnormal transitional stage B cell morphology	J:147840
	arteritis	J:147840
	decreased B cell proliferation	J:147840
	decreased marginal zone B cell number	J:147840
	enlarged lymph nodes	J:147840
	enlarged spleen	J:147840
	extramedullary hematopoiesis	J:147840
	glomerulonephritis	J:147840
	increased activated T cell number	J:147840
	increased anti-double stranded DNA antibody level	J:147840
	increased B cell apoptosis	J:147840
	increased B cell number	J:147840
	increased IgG2b level	J:147840
	increased immunoglobulin level	J:147840
	increased megakaryocyte cell number	J:147840
	increased spleen weight	J:147840
	increased susceptibility to systemic lupus erythematosus	J:147840
	intermingled spleen red and white pulp	J:147840
	kidney inflammation	J:147840
	premature death	J:147840
	renal fibrosis	J:147840
	renal glomerular protein deposits	J:147840
Cd19tm1(cre)Cgn/Cd19+ Ep300tm2Reck/Ep300+ involves: 129/Sv * 129P2/OlaHsd * FVB/N	increased susceptibility to systemic lupus erythematosus	J:147840
	premature death	J:147840
Ep300Plt6/Ep300Plt6 involves: 129S1/Sv * C57BL/6	decreased B cell number	J:140200
	decreased eosinophil cell number	J:140200
	decreased leukocyte cell number	J:140200
	decreased lymphocyte cell number	J:140200
	postnatal lethality	J:140200
	thrombocytosis	J:140200
Ep300tm1Dli/Ep300+ either: 129S4/SvJae or (involves: 129S4/SvJae * C57BL/6)	decreased embryo size	J:47301
	embryonic lethality during organogenesis, incomplete penetrance	J:47301
	exencephaly	J:47301
	open neural tube	J:47301
Ep300tm1Dli/Ep300+ involves: 129S4/SvJae * C57BL/6	normal hematopoietic system phenotype	J:60630
	normal neoplasm	J:60630
Ep300tm1Dli/Ep300tm1Dli either: 129S4/SvJae or (involves: 129S4/SvJae * C57BL/6)	abnormal cell physiology	J:47301
	abnormal vitelline vasculature morphology	J:47301
	absent trabeculae carneae	J:47301
	decreased cardiac muscle contractility	J:47301
	decreased embryo size	J:47301
	decreased fibroblast proliferation	J:47301
	early cellular replicative senescence	J:47301
	embryonic growth retardation	J:47301
	embryonic lethality during organogenesis, incomplete penetrance	J:47301
	enlarged heart	J:47301
	incomplete embryo turning	J:47301
	incomplete somite formation	J:47301
	pericardial effusion	J:47301
Ep300tm1Dli/Ep300tm1Dli involves: 129S4/SvJae * C57BL/6	abnormal facial morphology	J:47301
	decreased embryo size	J:47301
	embryonic growth arrest	J:47301
	embryonic lethality during organogenesis, complete penetrance	J:47301
	exencephaly	J:47301
	kinked neural tube	J:47301
	microphthalmia	J:47301
	open neural tube	J:47301
Ep300tm1Pkb/Ep300+ involves: 129P2/OlaHsd * C57BL/6	thrombocytosis	J:98329
Ep300tm1Pkb/Ep300tm1Pkb involves: 129P2/OlaHsd * C57BL/6	abnormal erythrocyte morphology	J:98329
	anemia	J:98329
	anisocytosis	J:98329
	decreased body size	J:98329
	decreased thymocyte number	J:98329
	increased megakaryocyte cell number	J:98329
	postnatal lethality, incomplete penetrance	J:98329
	thrombocytosis	J:98329
Ep300tm1Reck/Ep300+ involves: 129P2/OlaHsd	abnormal atrioventricular septum morphology	J:85949
	abnormal epicardium development	J:85949
	abnormal heart development	J:85949
	abnormal heart valve morphology	J:85949
	abnormal intestinal epithelium morphology	J:85949
	abnormal lung development	J:85949
	abnormal muscle fiber morphology	J:85950
	abnormal muscle morphology	J:85950
	abnormal myogenesis	J:85950
	abnormal small intestinal villus morphology	J:85949
	abnormal small intestine morphology	J:85949
	abnormal vasculogenesis	J:85949
	atrial septal defect	J:85949
	cyanosis	J:85949
	decreased body size	J:85949
	decreased skeletal muscle fiber size	J:85950
	delayed heart development	J:85949
	edema	J:85949, J:85950
	embryonic lethality during organogenesis, incomplete penetrance	J:85949, J:85950
	hemorrhage	J:85949
	internal hemorrhage	J:85949
	lethality throughout fetal growth and development, incomplete penetrance	J:85949, J:85950
	myocardium hypoplasia	J:85949
	perimembraneous ventricular septal defect	J:85949
	perinatal lethality, complete penetrance	J:85949, J:85950
	respiratory failure	J:85949
	thin myocardium	J:85949
	thin ventricle myocardium compact layer	J:85949
	thin ventricular wall	J:85949
	ventricular septal defect	J:85949
Ep300tm2Pkb/Ep300tm2Pkb Tg(Lck-cre)548Jxm/0 involves: 129P2/OlaHsd * C57BL/6 * CBA	decreased single-positive T cell number	J:105505
	decreased thymocyte number	J:105505
	increased double-positive T cell number	J:105505
	small thymus	J:105505
Ep300tm2Pkb/Ep300tm2Pkb Tg(MMTV-cre)4Mam/0 involves: 129P2/OlaHsd * FVB	normal neoplasm	J:105505
Ep300tm3Pkb/Ep300tm3Pkb involves: 129S6/SvEvTac * C57BL/6	postnatal lethality, incomplete penetrance	J:103607