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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Pknox1
Pbx/knotted 1 homeobox
MGI:1201409
12 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Atmtm1Fwa/Atmtm1Fwa
Pknox1tm1Fbla/Pknox1+
involves: 129S4/SvJae * C57BL/6
embryonic growth retardation J:165811
Atmtm1Fwa/Atmtm1Fwa
Pknox1tm1Fbla/Pknox1tm1Fbla
involves: 129S4/SvJae * C57BL/6
abnormal pluripotent precursor cell morphology J:165811
embryonic growth retardation J:165811
embryonic lethality between implantation and somite formation, incomplete penetrance J:165811
Cdkn2atm1.1Brn/Cdkn2atm1.1Brn
Pknox1tm1Fbla/Pknox1tm1Fbla
involves: 129/Sv * 129P2/OlaHsd * C57BL/6
abnormal pluripotent precursor cell morphology J:165811
Cdkn2atm1.1Brn/Cdkn2atm1.1Brn
Pknox1tm1Fbla/Pknox1tm1Fbla
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129/Sv * 129P2/OlaHsd * 129S2/SvPas * C57BL/6
preweaning lethality, complete penetrance J:165811
Pknox1tm1Fbla/Pknox1tm1Fbla
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S2/SvPas * C57BL/6
abnormal embryo development J:165811
abnormal embryonic epiblast morphology J:165811
abnormal extraembryonic endoderm formation J:165811
abnormal pluripotent precursor cell morphology J:165811
embryonic growth retardation J:165811
embryonic lethality, complete penetrance J:165811
Pknox1tm1Ngc/Pknox1+
Tg(IghMyc)22Bri/0
involves: C57BL * SJL
decreased B cell apoptosis J:192251
increased B cell derived lymphoma incidence J:192251
increased B cell proliferation J:192251
premature death J:192251

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory