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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Limk2
LIM domain kinase 2
MGI:1197517
28 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Limk2Gt(OST80053)Lex/Limk2Gt(OST80053)Lex
involves: 129S5/SvEvBrd * C57BL/6
abnormal cornea morphology J:192231
abnormal corneal epithelium morphology J:192231
abnormal eyelid development J:192231
decreased eye anterior chamber depth J:192231
eyelids open at birth J:192231
failure of eyelid fusion J:192231
increased incidence of corneal inflammation J:192231
retina neovascularization J:192231
Limk2tm1.1Tnak/Limk2tm1.1Tnak
either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * CD-1)
abnormal kidney morphology J:73966
abnormal spermatocyte morphology J:73966
abnormal spermatogenesis J:73966
decreased renal glomerulus number J:73966
decreased testis weight J:73966
dilated renal tubule J:73966
increased male germ cell apoptosis J:73966
small seminiferous tubules J:73966
Limk2tm1a(EUCOMM)Wtsi/Limk2+
C57BL/6N-Limk2tm1a(EUCOMM)Wtsi/Ics
abnormal locomotor activation J:165965
increased body weight J:165965
long tibia J:165965
Limk2whe/Limk2whe
B6.Cg-Lepob Limk2whe/GrsrJ
normal adipose tissue phenotype J:127016
anterior iris synechia J:127016
corneal opacity J:127016
corneal vascularization J:127016
early eyelid opening J:127016
normal hearing/vestibular/ear phenotype J:127016
increased incidence of corneal inflammation J:127016
increased inner canthal distance J:223062
short mandible J:127016
normal skeleton phenotype J:127016

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory