Prss12 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prss12
serine protease 12 neurotrypsin (motopsin)
MGI:1100881

10 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prss12^{em1(IMPC)Ccpcz}/Prss12^{em1(IMPC)Ccpcz} C57BL/6N-Prss12^{em1(IMPC)Ccpcz}/Ccpcz	abnormal eye morphology	J:211773
	abnormal thymus morphology	J:211773
	decreased body weight	J:211773
	enlarged thymus	J:211773
	increased circulating lactate dehydrogenase level	J:211773
Prss12^tm1Dgen/Prss12^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	decreased locomotor activity	J:101679
	increased thigmotaxis	J:101679
Prss12^tm1Mits/Prss12^tm1Mits B6.Cg-Prss12^tm1Mits	abnormal neuron physiology	J:157626
	abnormal social investigation	J:157626
	decreased dendritic spine density	J:157626

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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