54 phenotypes from 7 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gfra1tm1(cre/ERT2)Sjn/Gfra1tm1(cre/ERT2)Sjn involves: C57BL/6	absent kidney	J:199323
Gfra1tm1Bjh/Gfra1tm1Bjh either: (involves: 129S1/Sv * 129X1/SvJ * CD-1) or (involves: 129S1/Sv * 129X1/SvJ * Swiss Black)	abnormal digestion	J:60458
	abnormal digestive system morphology	J:60458
	abnormal enteric nervous system morphology	J:60458
	abnormal intestine morphology	J:60458
	abnormal kidney development	J:60458
	abnormal otic ganglion morphology	J:89887
	abnormal parasympathetic system morphology	J:89887
	abnormal pterygopalatine ganglion morphology	J:89887
	abnormal ureter morphology	J:60458
	absent kidney	J:60458
	absent ureter	J:60458
	neonatal lethality, complete penetrance	J:60458
Gfra1tm1Jmi/Gfra1+ involves: 129X1/SvJ * C57BL/6	abnormal enteric neuron morphology	J:82456
	abnormal neurotransmitter secretion	J:82456
	accelerated hair follicle regression	J:65034
	intestinal hypoperistalsis	J:82456
	thin skin	J:65034
Gfra1tm1Jmi/Gfra1tm1Jmi involves: 129X1/SvJ * C57BL/6	abnormal enteric ganglia morphology	J:49471
	abnormal enteric nervous system morphology	J:49471
	abnormal kidney morphology	J:49471
	abnormal ureteric bud invasion	J:49471
	abnormal ureteric bud morphology	J:49471
	abnormal urinary bladder morphology	J:49471
	absent kidney	J:49471
	neonatal lethality, complete penetrance	J:49471
Gfra1tm1Jmi/Gfra1tm2Jmi Tg(CAG-cre/Esr1*)5Amc/0 involves: 129/Sv * C57BL/6 * CBA * SJL	abnormal cell death	J:122607
	abnormal cell nucleus morphology	J:122607
	abnormal enteric ganglia morphology	J:122607
	abnormal enteric nervous system morphology	J:122607
	abnormal nervous system development	J:122607
	abnormal neuronal precursor proliferation	J:122607
	absent enteric neurons	J:122607
	normal nervous system phenotype	J:122607
Gfra1tm1Rosl/Gfra1tm1Rosl B6.129-Gfra1tm1Rosl	abnormal innervation pattern to muscle	J:78718
	abnormal spinal cord lateral motor column morphology	J:78718
	abnormal spinal nerve morphology	J:78718
	decreased motor neuron number	J:78718
Gfra1tm1Rosl/Gfra1tm1Rosl either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * CD-1)	abnormal enteric neuron morphology	J:68750
	abnormal kidney morphology	J:68750
	abnormal nodose ganglion morphology	J:68750
	abnormal somatic nervous system morphology	J:68750
	abnormal spinal nerve morphology	J:68750
	abnormal trigeminal nerve morphology	J:68750
	abnormal Wolffian duct morphology	J:68750
	absent enteric neurons	J:68750
	absent nephron	J:68750
	absent ureter	J:68750
	absent ureteric bud	J:68750
	normal behavior/neurological phenotype	J:68750
	decreased Peyer's patch number	J:120816
	loss of dopaminergic neurons	J:68750
	neonatal lethality, incomplete penetrance	J:68750
	small petrosal ganglion	J:68750
Gfra1tm2.1Jmi/Gfra1tm2.1Jmi involves: 129/Sv * C57BL/6 * CBA * SJL	abnormal enteric nervous system morphology	J:122607
	absent kidney	J:122607
	neonatal lethality, complete penetrance	J:122607
Gfra1tm2Jmi/Gfra1tm1(cre/ERT2)Sjn involves: 129X1/SvJ * C57BL/6	abnormal branching involved in ureteric bud morphogenesis	J:199323
	abnormal ureteric bud morphology	J:199323
	abnormal ureteric bud tip morphology	J:199323
	small kidney	J:199323
Gfra1tm2Jmi/Gfra1tm2Jmi Mnx1tm4(cre)Tmj/Mnx1+ involves: 129S1/Sv * 129X1/SvJ	decreased motor neuron number	J:132854
Gfra1tm2Jmi/Gfra1tm3Jmi Tg(Hoxb7-cre)13Amc/0 involves: 129X1/SvJ * C57BL/6	absent kidney	J:199323
	large ureter	J:199323
	single kidney	J:199323
Gfra1tm3Jmi/Gfra1tm3Jmi involves: 129X1/SvJ	abnormal motor neuron innervation pattern	J:132854
	abnormal motor neuron morphology	J:130616
	abnormal muscle spindle morphology	J:132854
	abnormal nervous system morphology	J:130616
	absent enteric neurons	J:130616
	absent kidney	J:130616
	decreased motor neuron number	J:132854
	impaired branching involved in ureteric bud morphogenesis	J:130616
	perinatal lethality, complete penetrance	J:130616