51 phenotypes from 6 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ighg1tm1(cre)Cgn/Ighg1+ Irf4tm1Rdf/Irf4tm1.1Rdf involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6	abnormal class switch recombination	J:112643
	abnormal memory B cell morphology	J:112643
	absent plasma cells	J:112643
	decreased IgG1 level	J:112643
	normal immune system phenotype	J:112643
Irf4em1(IMPC)Mbp/Irf4em1(IMPC)Mbp C57BL/6N-Irf4em1(IMPC)Mbp/MbpMmucd	abnormal lymph node morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal startle reflex	J:211773
	abnormal thymus morphology	J:211773
	decreased lymphocyte cell number	J:211773
	enlarged lymph nodes	J:211773
	enlarged spleen	J:211773
	enlarged thymus	J:211773
	increased neutrophil cell number	J:211773
	increased spleen weight	J:211773
Irf4m1Btlr/Irf4m1Btlr C57BL/6J-Irf4m1Btlr	abnormal B cell activation	J:160882
	decreased IgG level	J:160882
	decreased IgM level	J:160882
Irf4m1Btlr/Irf4m1Btlr involves: C57BL/6J	abnormal class switch recombination	J:185495
	decreased IgG level	J:185495
	decreased IgM level	J:185495
	normal immune system phenotype	J:185495
Irf4M2Btlr/Irf4+ C57BL/6J-Irf4M2Btlr	abnormal B cell activation	J:234245
	decreased IgG level	J:234245
	decreased IgM level	J:234245
Irf4M2Btlr/Irf4M2Btlr C57BL/6J-Irf4M2Btlr	abnormal B cell activation	J:234245
	decreased IgG level	J:234245
	decreased IgM level	J:234245
Irf4tm1.1Rdf/Irf4tm1.1Rdf involves: 129S1/Sv * 129S4/SvJae * C57BL/6	abnormal B cell differentiation	J:112643
	abnormal B cell physiology	J:112643
	absent spleen germinal center	J:112643
	decreased B cell proliferation	J:112643
	decreased IgG1 level	J:112643
Irf4tm1Mak/Irf4tm1Mak B6.129P2-Irf4tm1Mak	abnormal CD4-positive, alpha beta T cell morphology	J:78909
	abnormal T-helper 1 cell differentiation	J:78909
	increased susceptibility to bacterial infection	J:78909
Irf4tm1Mak/Irf4tm1Mak involves: 129P2/OlaHsd	abnormal B cell differentiation	J:42683
	abnormal immune system cell morphology	J:42683
	abnormal immune system physiology	J:42683
	abnormal lymph node morphology	J:42683
	abnormal spleen morphology	J:42683
	abnormal tumor susceptibility	J:42683
	absent lymph node germinal center	J:42683
	absent plasma cells	J:42683
	absent spleen germinal center	J:42683
	arrested B cell differentiation	J:42683
	decreased B cell proliferation	J:42683
	decreased dendritic cell number	J:91043
	decreased immunoglobulin level	J:42683
	decreased T cell proliferation	J:42683
	enlarged lymph nodes	J:42683
	enlarged spleen	J:42683
	normal immune system phenotype	J:169863
	increased lymphocyte cell number	J:42683
	increased susceptibility to Riboviria infection	J:42683
Irf4tm1Mak/Irf4tm1Mak involves: 129P2/OlaHsd * C57BL/6	decreased plasmacytoid dendritic cell number	J:97716
	increased susceptibility to bacterial infection	J:81744
Irf4tm1Rdf/Irf4tm1.1Rdf involves: 129S1/Sv * 129S4/SvJae * C57BL/6	normal immune system phenotype	J:112643
Irf4tm1Rdf/Irf4tm1.1Rdf involves: 129S1/Sv * 129S4/SvJae * C57BL/6	abnormal B cell physiology	J:112643
Irf4tm1Rdf/Irf4tm1Rdf Tg(Ucp1-cre)1Evdr/0 involves: 129S1/Sv * C57BL/6J * FVB	abnormal adipose tissue development	J:214637
	abnormal cellular respiration	J:214637
	decreased carbon dioxide production	J:214637
	decreased core body temperature	J:214637
	decreased fatty acid oxidation	J:214637
	decreased oxygen consumption	J:214637
	impaired adaptive thermogenesis	J:214637
	impaired glucose tolerance	J:214637
	impaired lipolysis	J:214637
	increased body fat mass	J:214637
	increased body weight	J:214637
	increased epididymal fat pad weight	J:214637
	increased inguinal fat pad weight	J:214637
	increased white fat cell size	J:214637
	insulin resistance	J:214637