Snai2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Snai2
snail family zinc finger 2
MGI:1096393

48 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sor^{tm3(Snai2)Jhai}/Gt(ROSA)26Sor⁺ Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr * CBA	embryonic lethality	J:194078
	hemorrhage	J:194078
	pallor	J:194078
Snai2^{tm1.1(KOMP)Vlcg}/Snai2⁺ C57BL/6N-Snai2^{tm1.1(KOMP)Vlcg}/Ucd	anophthalmia	J:211773
	enlarged heart	J:211773
	hemorrhage	J:211773
	microcephaly	J:211773
	microphthalmia	J:211773
	polydactyly	J:211773
	spina bifida	J:211773
	syndactyly	J:211773
Snai2^{tm1.1(KOMP)Vlcg}/Snai2^{tm1.1(KOMP)Vlcg} C57BL/6N-Snai2^{tm1.1(KOMP)Vlcg}/Ucd	abnormal coat/ hair morphology	J:211773
	abnormal coat/hair pigmentation	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Snai2^tm1Grid/Snai2^tm1Grid involves: 129S1/Sv	decreased body size	J:48521
Snai2^tm1Grid/Snai2^tm1Grid involves: 129S1/Sv * C57BL/6J	abnormal cardiac epithelial to mesenchymal transition	J:139512
	abnormal fetal atrioventricular canal morphology	J:139512
	decreased atrioventricular cushion size	J:139512
Snai2^tm1Look/Snai2^tm1Look involves: 129X1/SvJ * C57BL/6	abnormal hematopoietic system morphology/development	J:80652
	blepharitis	J:80652
	normal hematopoietic system phenotype	J:80652
	normal immune system phenotype	J:80652
	increased mortality induced by gamma-irradiation	J:80652
	postnatal growth retardation	J:80652
Snai2^tm2Grid/Snai2^tm2Grid involves: 129S1/Sv	abnormal conjunctiva morphology	J:48521
	abnormal skin pigmentation	J:78323
	abnormal T cell differentiation	J:78323
	blepharitis	J:48521
	circling	J:78323, J:80529
	conjunctivitis	J:48521
	decreased body size	J:48521
	decreased forehead pigmentation	J:80529
	decreased hematocrit	J:78323
	decreased hemoglobin content	J:78323
	decreased leukocyte cell number	J:78323
	decreased litter size	J:78323
	diluted coat color	J:78323
	head blaze	J:78323
	hyperactivity	J:78323, J:80529
	increased mean corpuscular volume	J:78323
	macrocytic anemia	J:78323
	male infertility	J:78323
	postnatal growth retardation	J:48521
	reduced male fertility	J:78323
	small seminiferous tubules	J:78323
	small testis	J:78323
	small thymus	J:78323
	thrombocytopenia	J:78323
	variable body spotting	J:78323, J:80529
Snai2^tm2Grid/Snai2^tm2Grid involves: 129S1/Sv * C57BL/6	cleft secondary palate	J:121243
	neonatal lethality, incomplete penetrance	J:121243
	persistence of medial edge epithelium during palatal shelf fusion	J:121243

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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