Abcb7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Abcb7
ATP-binding cassette, sub-family B member 7
MGI:109533

18 phenotypes from 2 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Abcb7^tm1.1Mdf/Abcb7⁺ involves: 129S4/SvJae * FVB	genetic imprinting	J:106838
Abcb7^tm1.1Mdf/Abcb7⁺ involves: 129S4/SvJae * FVB	prenatal lethality	J:106838
Abcb7^tm1.1Mdf/Y involves: 129S4/SvJae * FVB	prenatal lethality	J:106838
Abcb7^tm1Mdf/Abcb7⁺ Tg(Gata1-cre)1Sho/0 either: (involves: 129S4/SvJae * 129S6/SvEvTac * FVB/N) or (involves: 129S4/SvJae * C57BL/6J * FVB/N)	abnormal ectoplacental cone morphology	J:106838
	embryonic growth retardation	J:106838
	embryonic lethality between implantation and somite formation, complete penetrance	J:106838
	hemorrhage	J:106838
Abcb7^tm1Mdf/Abcb7⁺ Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ either: B6.Cg-Edil3^{Tg(Sox2-cre)1Amc} Abcb7^tm1Mdf or (involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * CBA)	normal mortality/aging	J:106838
Abcb7^tm1Mdf/Abcb7⁺ Tg(Vil1-cre)20Syr/0 either: (involves: 129S4/SvJae * C57BL/6 * DBA/2) or (involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * DBA/2)	prenatal lethality, complete penetrance	J:106838
Abcb7^tm1Mdf/Y Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ either: B6.Cg-Edil3^{Tg(Sox2-cre)1Amc} Abcb7^tm1Mdf or (involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * CBA)	embryonic lethality between somite formation and embryo turning, complete penetrance	J:106838
Abcb7^tm1Mdf/Y Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ either: B6.Cg-Speer6-ps1^{Tg(Alb-cre)21Mgn} Abcb7^tm1Mdf or (involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * DBA)	abnormal circulating enzyme level	J:106838
	abnormal enzyme/coenzyme activity	J:106838
	abnormal hepatocyte mitochondrial morphology	J:106838
	abnormal hepatocyte morphology	J:106838
	abnormal liver morphology	J:106838
	hemosiderosis	J:106838
Abcb7^tm1Mdf/Y Tg(Gata1-cre)1Sho/0 either: (involves: 129S4/SvJae * 129S6/SvEvTac * FVB/N) or (involves: 129S4/SvJae * C57BL/6J * FVB/N)	abnormal ectoplacental cone morphology	J:106838
	embryonic growth retardation	J:106838
	embryonic lethality between implantation and somite formation, complete penetrance	J:106838
	hemorrhage	J:106838
Abcb7^tm1Mdf/Y Tg(Nes-cre)1Kln/0 either: B6.Cg-Tg(Nes-cre)1Kln Abcb7^tm1Mdf or (involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * SJL)	neonatal lethality, incomplete penetrance	J:106838
	normal nervous system phenotype	J:106838
	postnatal lethality, complete penetrance	J:106838
Abcb7^tm1Mdf/Y Tg(Vil1-cre)20Syr/0 either: (involves: 129S4/SvJae * C57BL/6 * DBA/2) or (involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * DBA/2)	prenatal lethality, complete penetrance	J:106838

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23