Trpc3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trpc3
transient receptor potential cation channel, subfamily C, member 3
MGI:109526

15 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Trpc3^Mwk/Trpc3⁺ involves: BALB/cAnN * C3H/HeH	abnormal gait	J:148340
	abnormal nervous system electrophysiology	J:148340
	abnormal Purkinje cell dendrite morphology	J:148340
	abnormal Purkinje cell morphology	J:148340
	decreased body size	J:148340
	decreased Purkinje cell number	J:148340
	impaired balance	J:148340
Trpc3^Mwk/Trpc3^Mwk involves: BALB/cAnN * C3H/HeH	premature death	J:148340
Trpc3^tm1.1Akon/Trpc3^tm1.1Akon involves: 129S/SvEv	abnormal eye physiology	J:176849
Trpc3^tm1.1Akon/Trpc3^tm1.1Akon involves: 129S/SvEv * 129S4/SvJaeSor	abnormal excitatory postsynaptic currents	J:139695
	abnormal gait	J:139695
	impaired limb coordination	J:139695
	normal nervous system phenotype	J:139695
Trpc3^tm1.1Bmil/Trpc3^tm1.1Bmil involves: FVB/N	normal hematopoietic system phenotype	J:189490
Trpc3^tm1.2Akon/Trpc3^tm1.2Akon involves: 129S/SvEv	normal immune system phenotype	J:190105
Trpc3^{tm1b(EUCOMM)Wtsi}/Trpc3^{tm1b(EUCOMM)Wtsi} C57BL/6N-Trpc3^{tm1b(EUCOMM)Wtsi}/Rbrc	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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