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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Atf2
activating transcription factor 2
MGI:109349
29 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Atf2Tg(Gzma-Klra1)7Wum/Atf2+
involves: C57BL/6
abnormal artery development J:134875
abnormal NK cell physiology J:61178
decreased circulating interferon-gamma level J:61178
decreased NK cell number J:61178
decreased NK T cell number J:61178
normal immune system phenotype J:61178
increased metastatic potential J:61178
Atf2tm1Nicj/Atf2tm1Nicj
Atf7tm1Nicj/Atf7tm1Nicj
involves: 129P2/OlaHsd * C57BL/6
abnormal common myeloid progenitor cell morphology J:123909
anemia J:123909
embryonic growth arrest J:123909
embryonic growth retardation J:123909
embryonic lethality during organogenesis, complete penetrance J:123909
Atf2tm1Sis/Atf2+
Creb5tm1Sis/Creb5+
involves: C57BL/6 * CBA
abnormal cell differentiation J:156376
normal adipose tissue phenotype J:156376
normal behavior/neurological phenotype J:156376
decreased subcutaneous adipose tissue amount J:156376
decreased white adipose tissue amount J:156376
decreased white fat cell size J:156376
normal growth/size/body region phenotype J:156376
improved glucose tolerance J:156376
increased insulin sensitivity J:156376
increased oxygen consumption J:156376
Atf2tm1Sis/Atf2tm1Sis
Creb5tm1Sis/Creb5tm1Sis
involves: C57BL/6 * CBA
abnormal cell differentiation J:156376
Atf2tm2Nicj/Atf2tm2Nicj
Atf7tm1Nicj/Atf7tm1Nicj
involves: 129P2/OlaHsd * C57BL/6
abnormal common myeloid progenitor cell morphology J:123909
abnormal liver morphology J:123909
anemia J:123909
decreased cell proliferation J:123909
embryonic growth arrest J:123909
embryonic growth retardation J:123909
embryonic lethality during organogenesis, complete penetrance J:123909
heart hypoplasia J:123909
hemopericardium J:123909
increased apoptosis J:123909
increased hepatocyte apoptosis J:123909
liver hypoplasia J:123909

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory