Rgs16 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rgs16
regulator of G-protein signaling 16
MGI:108407

21 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rgs16^tm1.1Drue/Rgs16^tm1.1Drue involves: C57BL/6	abnormal T-helper 1 physiology	J:188966
	abnormal T-helper 2 physiology	J:188966
	granulomatous inflammation	J:188966
	increased interleukin-5 secretion	J:188966
	increased interleukin-10 secretion	J:188966
	increased interleukin-13 secretion	J:188966
	increased susceptibility to parasitic infection	J:188966
	pulmonary fibrosis	J:188966
Rgs16^tm1Sia/Rgs16^tm1Sia B6.Cg-Rgs16^tm1Sia	prolonged circadian behavior period	J:205653
Rgs16^tm1Tmw/Rgs16^tm1Tmw involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6	increased circulating ketone body level	J:172091
	increased fatty acid oxidation	J:172091
Tg(APOE-rtTAM2,tetO-Rgs16)#Tmw/0 involves: C57BL/6 DBA	decreased circulating cholesterol level	J:172091
	decreased circulating glucose level	J:172091
	decreased circulating ketone body level	J:172091
	decreased fatty acid oxidation	J:172091
	hepatic steatosis	J:172091
	increased circulating triglyceride level	J:172091
	increased liver triglyceride level	J:172091
Tg(CMV-EGFP,RNU6-RNAi:Rgs16)#Haya/0 involves: C57BL/6J	abnormal eating behavior	J:171718
	decreased locomotor activity	J:171718
	shortened circadian behavior period	J:171718

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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