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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ccr4
chemokine (C-C motif) receptor 4
MGI:107824
30 phenotypes from 1 allele in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ccr4tm1Pwr/Ccr4tm1Pwr
B6.129P2-Ccr4tm1Pwr
increased CD8-positive, alpha-beta T cell number J:95239
increased length of allograft survival J:95239
increased NK T cell number J:95239
Ccr4tm1Pwr/Ccr4tm1Pwr
involves: 129P2/OlaHsd * C57BL/6
abnormal chemokine secretion J:70088
abnormal cytokine secretion J:120221
abnormal splenocyte physiology J:70088
decreased airway resistance J:120221
decreased eosinophil cell number J:120221
decreased IgE level J:120221
decreased interleukin-1 beta secretion J:70088
decreased interleukin-4 secretion J:120221
decreased interleukin-5 secretion J:120221
decreased interleukin-10 secretion J:120221
decreased interleukin-13 secretion J:120221
decreased lymphocyte cell number J:70088
decreased macrophage cell number J:70088
decreased susceptibility to endotoxin shock J:70088
decreased susceptibility to fungal infection J:120221
decreased tumor necrosis factor secretion J:70088
normal immune system phenotype J:70088
increased airway resistance J:120221
increased IgE level J:120221
increased IgG1 level J:120221
increased interferon-gamma secretion J:120221
increased interleukin-4 secretion J:120221
increased interleukin-5 secretion J:120221
increased interleukin-10 secretion J:120221
increased macrophage cell number J:120221
increased neutrophil cell number J:120221
increased tumor necrosis factor secretion J:120221

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory