Ccr4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ccr4
C-C motif chemokine receptor 4
MGI:107824

30 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ccr4^tm1Pwr/Ccr4^tm1Pwr B6.129P2-Ccr4^tm1Pwr	increased CD8-positive, alpha-beta T cell number	J:95239
	increased length of allograft survival	J:95239
	increased NK T cell number	J:95239
Ccr4^tm1Pwr/Ccr4^tm1Pwr involves: 129P2/OlaHsd * C57BL/6	abnormal chemokine secretion	J:70088
	abnormal cytokine secretion	J:120221
	abnormal splenocyte physiology	J:70088
	decreased airway resistance	J:120221
	decreased eosinophil cell number	J:120221
	decreased IgE level	J:120221
	decreased interleukin-1 beta secretion	J:70088
	decreased interleukin-4 secretion	J:120221
	decreased interleukin-5 secretion	J:120221
	decreased interleukin-10 secretion	J:120221
	decreased interleukin-13 secretion	J:120221
	decreased lymphocyte cell number	J:70088
	decreased macrophage cell number	J:70088
	decreased susceptibility to endotoxin shock	J:70088
	decreased susceptibility to fungal infection	J:120221
	decreased tumor necrosis factor secretion	J:70088
	normal immune system phenotype	J:70088
	increased airway resistance	J:120221
	increased IgE level	J:120221
	increased IgG1 level	J:120221
	increased interferon-gamma secretion	J:120221
	increased interleukin-4 secretion	J:120221
	increased interleukin-5 secretion	J:120221
	increased interleukin-10 secretion	J:120221
	increased macrophage cell number	J:120221
	increased neutrophil cell number	J:120221
	increased tumor necrosis factor secretion	J:120221

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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