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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Mesp1
mesoderm posterior 1
MGI:107785
30 phenotypes from 4 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Mesp1/Mesp2tm1Ysa/Mesp1/Mesp2tm1Ysa
involves: C57BL/6 * CBA * ICR
abnormal blood vessel morphology J:62984
abnormal ectoderm development J:62984
abnormal endoderm development J:62984
abnormal gastrulation J:62984
abnormal mesoderm development J:62984
abnormal primitive streak formation J:62984
absent heart J:62984
absent mesoderm J:62984
absent paraxial mesoderm J:62984
absent somites J:62984
decreased embryo size J:62984
embryonic lethality during organogenesis, complete penetrance J:62984
Mesp1tm1Ysa/Mesp1tm3Ysa
involves: C57BL/6 * CBA * ICR
abnormal mesoderm development J:55840
abnormal primitive streak morphology J:55840
Mesp1tm3Ysa/Mesp1tm3Ysa
involves: C57BL/6 * CBA
abnormal cardiogenic mesoderm morphology J:55840
abnormal heart development J:49903, J:55840
abnormal heart looping J:49903, J:55840
abnormal heart tube morphology J:55840
abnormal mesoderm development J:55840
abnormal neural fold formation J:49903
abnormal neural tube morphology J:49903
abnormal paraxial mesoderm morphology J:55840
abnormal primitive streak morphology J:55840
cardia bifida J:49903, J:55840
decreased embryo size J:49903
decreased somite size J:49903
delayed embryo turning J:49903
delayed neural tube closure J:49903
embryonic growth arrest J:49903, J:55840
embryonic growth retardation J:49903, J:55840
embryonic lethality during organogenesis, complete penetrance J:49903, J:55840
failure of initiation of embryo turning J:49903
microcephaly J:49903
Mesp1tm4Ysa/Mesp1tm4Ysa
involves: C57BL/6 * CBA * ICR
absent heart J:71983
absent somites J:71983
disorganized embryonic tissue J:71983
prenatal lethality, complete penetrance J:71983

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory