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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ly6a
lymphocyte antigen 6 complex, locus A
MGI:107527
38 phenotypes from 3 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ly6atm1Grau/Ly6a+
involves: 129X1/SvJ * C57BL/6
no abnormal phenotype detected J:82052
Ly6atm1Grau/Ly6atm1Grau
involves: 129X1/SvJ * C57BL/6
no abnormal phenotype detected J:82052
Ly6atm1Pmf/Ly6atm1Pmf
B6.129P2-Ly6atm1Pmf
abnormal common myeloid progenitor cell morphology J:81387
abnormal definitive hematopoiesis J:81387
abnormal immunoglobulin level J:42594
abnormal myeloid leukocyte morphology J:81387
abnormal T cell proliferation J:42594
decreased granulocyte number J:81387
decreased megakaryocyte cell number J:81387
decreased monocyte cell number J:81387
increased bleeding time J:81387
increased lymphocyte cell number J:81387
normal mortality/aging J:42594
thrombocytopenia J:81387
Ly6atm1Pmf/Ly6atm1Pmf
C.129P2-Ly6atm1Pmf
abnormal common myeloid progenitor cell morphology J:83409
abnormal fat cell morphology J:83409
abnormal osteoblast differentiation J:83409
abnormal osteoblast physiology J:83409
abnormal osteoclast differentiation J:83409
decreased bone mineral content J:83409
decreased bone ossification J:83409
decreased bone strength J:83409
decreased bone trabecula number J:83409
decreased osteoclast cell number J:83409
decreased osteoid volume J:83409
osteoporosis J:83409
Ly6atm1Pmf/Ly6atm1Pmf
involves: 129P2/OlaHsd * C57BL/6
prenatal lethality, complete penetrance J:42594
Ly6atm2(RUNX1)Grau/Ly6a+
involves: 129X1/SvJ * C57BL/6J
abnormal spleen B cell follicle morphology J:93408
absent common myeloid progenitor cells J:93408
enlarged spleen J:93408
epidermal hyperplasia J:93408
extramedullary hematopoiesis J:93408
hyperkeratosis J:93408
increased erythroid progenitor cell number J:93408
increased leukocyte cell number J:93408
increased neutrophil cell number J:93408
increased squamous cell carcinoma incidence J:93408
myeloid hyperplasia J:93408
polychromatophilia J:93408
spontaneous skin ulceration J:93408

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory