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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gata6
GATA binding protein 6
MGI:107516
42 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gata4tm1.1Sad/Gata4+
Gata6tm2.1Sad/Gata6tm2.1Sad
Tg(Wt1-cre)1Jbeb/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal heart layer morphology J:206877
preweaning lethality, incomplete penetrance J:206877
Gata4tm1.1Sad/Gata4tm1.1Sad
Gata6tm2.1Sad/Gata6+
Tg(Wt1-cre)1Jbeb/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal heart layer morphology J:206877
preweaning lethality, incomplete penetrance J:206877
Gata4tm1.1Sad/Gata4tm1.1Sad
Gata6tm2.1Sad/Gata6tm2.1Sad
Tg(Wt1-cre)1Jbeb/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal cardiovascular development J:206877
abnormal heart layer morphology J:206877
decreased fetal cardiomyocyte proliferation J:206877
lethality throughout fetal growth and development, complete penetrance J:206877
polydactyly J:206877
thin myocardium J:206877
thin ventricular wall J:206877
Gata4tm1.2Sad/Gata4tm1.2Sad
Gata6tm3.1Sad/Gata6tm3.1Sad
involves: 129 		abnormal cardiogenic mesoderm morphology J:135185
abnormal fetal cardiomyocyte morphology J:135185
absent heart J:135185
absent heart tube J:135185
Gata4tm1Eno/Gata4+
Gata6tm1Eno/Gata6+
involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 		abnormal aorta morphology J:111824
abnormal aorta smooth muscle morphology J:111824
abnormal blood vessel morphology J:111824
abnormal cardiac outflow tract development J:111824
abnormal fetal cardiomyocyte proliferation J:111824
abnormal interventricular septum morphology J:111824
abnormal vascular smooth muscle morphology J:111824
aorta hypoplasia J:111824
aortic arch hypoplasia J:111824
decreased erythrocyte cell number J:111824
dilated aorta J:111824
edema J:111824
embryonic lethality during organogenesis, complete penetrance J:111824
hemorrhage J:111824
irregular heartbeat J:111824
persistent truncus arteriosus J:111824
small liver J:111824
thin myocardium J:111824
thin myocardium compact layer J:111824
ventricular septal defect J:111824
Gata4tm1Sho/Gata4tm1Sho
Gata6tm1Kgac/Gata6tm1Kgac
involves: 129S1/Sv * 129S6/SvEvTac 		abnormal lung development J:134027
Gata6tm1Msp/Gata6+
Nkx2-1tm1Shk/Nkx2-1+
involves: 129S4/SvJae * 129X1/SvJ * C57BL/6 * CD-1 		abnormal lung development J:117072
abnormal lung epithelium morphology J:117072
abnormal lung saccule morphology J:117072
abnormal pulmonary alveolus epithelium morphology J:117072
absent alveolar lamellar bodies J:117072
decreased surfactant secretion J:117072
postnatal lethality, incomplete penetrance J:117072
thick lung-associated mesenchyme J:117072
Gata6tm2.1Sad/Gata6tm2.1Sad
Gli1tm1Alj/Gli1tm1Alj
Tg(Prrx1-cre)1Cjt/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J 		polydactyly J:205405
Gata6tm2.1Sad/Gata6tm2.1Sad
Shhtm2Amc/Shhtm2Amc
Tg(Prrx1-cre)1Cjt/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J 		hindlimb oligodactyly J:205405
Gata6tm2.2Sad/Gata6tm2.2Sad
Pdgfratm11(EGFP)Sor/Pdgfra+
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ 		absent primitive endoderm J:213580
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Tg(Prrx1-cre)1Cjt/0
Tg(tetO-Gata6)1Abl/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J 		oligodactyly J:205405
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory