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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Plcb4
phospholipase C, beta 4
MGI:107464
31 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Plcb4tm1b(EUCOMM)Wtsi/Plcb4tm1b(EUCOMM)Wtsi
C57BL/6N-Plcb4tm1b(EUCOMM)Wtsi/Tcp
abnormal gait J:211773
abnormal gallbladder morphology J:211773
abnormal locomotor behavior J:211773
decreased body length J:211773
decreased lean body mass J:211773
decreased total body fat amount J:211773
enlarged gallbladder J:211773
hydrometra J:211773
hypoactivity J:211773
increased bone mineral content J:211773
increased grip strength J:211773
increased lean body mass J:211773
increased or absent threshold for auditory brainstem response J:211773
small superior vagus ganglion J:211773
Plcb4tm1Dwu/Plcb4tm1Dwu
involves: 129S1/Sv
abnormal locomotor coordination J:51664
abnormal Purkinje cell innervation J:51664
abnormal rod electrophysiology J:77638
abnormal vision J:77638
ataxia J:51664
impaired coordination J:51664
short stride length J:51664
Plcb4tm1Hssh/Plcb4tm1Hssh
Not Specified
abnormal cerebellar foliation J:43077
abnormal cerebellum external granule cell layer morphology J:43077
abnormal gait J:43077
abnormal synaptic transmission J:43077
ataxia J:43077
decreased body size J:43077
hypoactivity J:43077
normal muscle phenotype J:43077
postnatal lethality, incomplete penetrance J:43077
normal skeleton phenotype J:43077
small cerebellum J:43077
Plcb4tm1Tyo/Plcb4tm1Tyo
involves: C57BL/6J
abnormal nervous system physiology J:72939
reduced long term depression J:72939

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory