Ctss Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ctss
cathepsin S
MGI:107341

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ctss^tm1Hap/Ctss^tm1Hap Dmd^mdx/Dmd^mdx involves: 129S2/SvPas * C57BL/10ScSn	abnormal skeletal muscle fiber morphology	J:230788
	centrally nucleated skeletal muscle fibers	J:230788
	dystrophic muscle	J:230788
	impaired exercise endurance	J:230788
	increased circulating creatine kinase level	J:230788
	skeletal muscle fiber necrosis	J:230788
	skeletal muscle fibrosis	J:230788
Ctss^tm1Hap/Ctss^tm1Hap Ldlr^tm1Her/Ldlr^tm1Her B6.129S-Ctss^tm1Hap Ldlr^tm1Her	abnormal leukocyte migration	J:82520
	decreased circulating cholesterol level	J:82520
	decreased circulating LDL cholesterol level	J:82520
	decreased susceptibility to atherosclerosis	J:82520
	vascular smooth muscle hypoplasia	J:82520
Ctss^tm1Hap/Ctss^tm1Hap Tg(Scgb1a1-rtTA,tetO-Ifng)14Eli/0 involves: 129S2/SvPas * C57BL/6 * CBA	abnormal lung volume	J:100854
	emphysema	J:100854
	increased apoptosis	J:100854
	increased lung compliance	J:100854
	increased lymphocyte cell number	J:100854
	increased macrophage cell number	J:100854
	increased neutrophil cell number	J:100854

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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