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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Phox2a
paired-like homeobox 2a
MGI:106633
39 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Phox2a/Inppl1tm1Ssch/Phox2a+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal glycogen homeostasis J:96443
decreased body weight J:96443
improved glucose tolerance J:96443
Phox2a/Inppl1tm1Ssch/Phox2a/Inppl1tm1Ssch
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal gluconeogenesis J:96443
cyanosis J:96443
decreased circulating insulin level J:96443
hypoglycemia J:96443
increased insulin sensitivity J:96443
lethargy J:96443
postnatal growth retardation J:96443
postnatal lethality, complete penetrance J:96443
respiratory distress J:96443
Phox2atm1(Phox2b)Mist/Phox2atm1(Phox2b)Mist
involves: 129S2/SvPas
abnormal oculomotor nerve morphology J:126634
abnormal trochlear nerve morphology J:126634
normal mortality/aging J:126634
normal nervous system phenotype J:126634
Phox2atm1.1Sgu/Phox2atm1.1Sgu
involves: 129P2/OlaHsd * C57BL/6
abnormal autonomic nervous system morphology J:63720
abnormal cranial ganglia morphology J:63720
abnormal facial nerve morphology J:63720
abnormal locus ceruleus morphology J:63720
abnormal otic ganglion morphology J:63720
abnormal parasympathetic ganglion morphology J:63720
abnormal pterygopalatine ganglion morphology J:63720
abnormal respiration J:89905
decreased pulmonary respiratory rate J:89905
small geniculate ganglion J:63720
small nodose ganglion J:63720
small petrosal ganglion J:63720
small submandibular ganglion J:63720
small superior cervical ganglion J:63720
small trigeminal ganglion J:63720
Phox2atm1.1Sgu/Phox2atm1.1Sgu
involves: 129P2/OlaHsd * C57BL/6J
abnormal neuron differentiation J:175535
decreased motor neuron number J:175535
increased neuron number J:175535
Phox2atm1Jbr/Phox2a+
involves: 129P2/OlaHsd * C57BL/6
increased pulmonary respiratory rate J:121653
increased pulmonary ventilation J:121653
increased tidal volume J:121653
Phox2atm1Jbr/Phox2atm1Jbr
involves: 129P2/OlaHsd
abnormal facial nerve morphology J:157532
abnormal pterygopalatine ganglion morphology J:157532
abnormal sublingual ganglion morphology J:157532
abnormal submandibular ganglion morphology J:157532
Phox2atm1Jbr/Phox2atm1Jbr
involves: 129P2/OlaHsd * C57BL/6
abnormal autonomic nervous system morphology J:39084
abnormal cranial ganglia morphology J:39084
abnormal locus ceruleus morphology J:39084
abnormal otic ganglion morphology J:39084
abnormal parasympathetic ganglion morphology J:39084
abnormal pterygopalatine ganglion morphology J:39084
small geniculate ganglion J:39084
small nodose ganglion J:39084
small petrosal ganglion J:39084
small submandibular ganglion J:39084
small superior cervical ganglion J:39084
Phox2atm2.1Jbr/Phox2atm2.1Jbr
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S2/SvPas * C57BL/6J * CBA/J
normal nervous system phenotype J:157532

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory