45 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pdcd1tm1.1Liux/Pdcd1tm1.1Liux involves: C57BL/6	decreased cell proliferation	J:190150
	decreased regulatory T cell number	J:190150
	decreased susceptibility to induced morbidity/mortality	J:190150
	decreased tumor growth/size	J:190150
	increased apoptosis	J:190150
	increased T-helper 1 cell number	J:190150
Pdcd1tm1.1Shr/Pdcd1tm1.1Shr involves: C57BL/6	decreased B-1 B cell number	J:153040
	increased regulatory T cell number	J:153040
	increased retina ganglion cell number	J:154546
Pdcd1tm1Hon/Pdcd1tm1Hon B6.129S2-Pdcd1tm1Hon	abnormal response to transplant	J:119356
	arthritis	J:78802
	glomerulonephritis	J:78802
Pdcd1tm1Hon/Pdcd1tm1Hon C.129S2(B6)-Pdcd1tm1Hon	abnormal cardiac muscle contractility	J:66979
	abnormal cardiac output	J:66979
	abnormal cardiovascular system physiology	J:66979
	abnormal heart morphology	J:66979
	cardiac fibrosis	J:66979
	decreased heart right ventricle wall thickness	J:66979
	dilated heart ventricle	J:66979
	enlarged heart	J:66979
	enlarged liver	J:66979
	exophthalmos	J:66979
	increased autoantibody level	J:66979
	premature death	J:66979
Pdcd1tm1Hon/Pdcd1tm1Hon involves: 129S2/SvPas	abnormal T cell activation	J:222944
	hepatic necrosis	J:222944
	increased IgA level	J:222944
	increased IgM level	J:222944
	increased inflammatory response	J:222944
	increased interferon-gamma secretion	J:222944
	pancreas necrosis	J:222944
	pulmonary necrosis	J:222944
Pdcd1tm1Hon/Pdcd1tm1Hon involves: 129S2/SvPas * C57BL/6	abnormal immunoglobulin level	J:50688
	abnormal leukopoiesis	J:50688
	abnormal myelopoiesis	J:50688
	enlarged spleen	J:50688
	increased B cell number	J:50688
	increased B cell proliferation	J:50688
	increased B-1 B cell number	J:50688
	increased IgA level	J:50688
	increased IgG2b level	J:50688
	increased IgG3 level	J:50688
	increased lymphocyte cell number	J:50688
Pdcd1tm1Llc/Pdcd1tm1Llc involves: 129S5/SvEvBrd	abnormal cytokine secretion	J:126829
	decreased CD8-positive, alpha-beta T cell number	J:126829
	increased susceptibility to experimental autoimmune encephalomyelitis	J:126829