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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Col4a3
collagen, type IV, alpha 3
MGI:104688
48 phenotypes from 4 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Col4a3tm1.1Rkl/Col4a3+
involves: C57BL/6
abnormal renal glomerulus morphology J:167404
glomerulonephritis J:167404
increased circulating creatinine level J:167404
increased urine protein level J:167404
kidney atrophy J:167404
podocyte foot process effacement J:167404
premature death J:167404
renal interstitial fibrosis J:167404
Col4a3tm1b(EUCOMM)Wtsi/Col4a3tm1b(EUCOMM)Wtsi
C57BL/6N-Col4a3tm1b(EUCOMM)Wtsi/H
decreased circulating amylase level J:211773
decreased circulating bilirubin level J:211773
irregularly shaped pupil J:211773
Col4a3tm1Dec/Col4a3tm1Dec
129-Col4a3tm1Dec/J
abnormal renal glomerulus basement membrane morphology J:158731
abnormal renal glomerulus morphology J:158731
albuminuria J:158731
decreased survivor rate J:158731
glomerulonephritis J:158731
glomerulosclerosis J:158731
glomerulus hemorrhage J:158731
increased blood urea nitrogen level J:158731
increased circulating creatinine level J:158731
increased renal glomerulus basement membrane thickness J:158731
increased urine protein level J:158731
kidney failure J:158731
premature death J:158731
renal cast J:158731
renal interstitial fibrosis J:158731
renal tubule atrophy J:158731
Col4a3tm1Dec/Col4a3tm1Dec
129X1/SvJ-Col4a3tm1Dec
abnormal cochlear basement membrane morphology J:91619, J:98449
abnormal stria vascularis morphology J:98449
abnormal stria vascularis vasculature morphology J:91619
increased or absent threshold for auditory brainstem response J:91619
sensorineural hearing loss J:91619
Col4a3tm1Dec/Col4a3tm1Dec
B6.129X1-Col4a3tm1Dec
abnormal renal glomerulus basement membrane thickness J:167404
glomerulonephritis J:167404
increased circulating creatinine level J:167404
increased urine protein level J:167404
podocyte foot process effacement J:167404
premature death J:167404
renal interstitial fibrosis J:167404
renal tubule atrophy J:167404
Col4a3tm1Dec/Col4a3tm1Dec
involves: 129X1/SvJ * C57BL/6
abnormal cochlear basement membrane morphology J:91619
abnormal glomerular capillary morphology J:37963
abnormal lens morphology J:37963
abnormal membranous labyrinth morphology J:91619
abnormal podocyte morphology J:37963
abnormal renal glomerulus basement membrane thickness J:37963
abnormal stria vascularis morphology J:91619
abnormal stria vascularis vasculature morphology J:91619
abnormal strial marginal cell morphology J:91619
albuminuria J:37963
expanded mesangial matrix J:37963
glomerulonephritis J:37963
granular kidney J:37963
hematuria J:37963
increased blood urea nitrogen level J:37963
mesangial cell hyperplasia J:37963
pale kidney J:37963
podocyte foot process effacement J:37963, J:91619
podocyte microvillus transformation J:37963
premature death J:37963
renal glomerulus fibrosis J:37963
small kidney J:37963
Col4a3tm1Jhm/Col4a3tm1Jhm
involves: 129S1/Sv * 129X1/SvJ
abnormal glomerular capillary morphology J:37017
abnormal kidney morphology J:37017
abnormal podocyte foot process morphology J:207595
abnormal renal glomerulus basement membrane morphology J:37017, J:207595
albuminuria J:37017
decreased body weight J:37017
decreased renal glomerular filtration rate J:37017
expanded mesangial matrix J:37017
glomerular crescent J:37017
glomerulonephritis J:37017
glomerulosclerosis J:37017, J:207595
increased blood urea nitrogen level J:37017
increased circulating creatinine level J:37017
increased or absent threshold for auditory brainstem response J:37017
increased renal glomerulus basement membrane thickness J:37017, J:207595
increased urine protein level J:37017, J:207595
kidney failure J:37017
lethargy J:37017
polyuria J:37017
premature death J:37017, J:207595
renal cast J:207595
renal tubule atrophy J:37017
small kidney J:37017
uremia J:37017

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory