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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tfeb
transcription factor EB
MGI:103270
15 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tfebem1Xinli/Tfebem1Xinli
involves: C57BL/6J 		normal growth/size/body region phenotype J:342735
increased susceptibility to bacterial infection induced morbidity/mortality J:342735
normal mortality/aging J:342735
TfebGt(PT1-ATG)213Wrst/TfebGt(PT1-ATG)213Wrst
involves: 129S1/Sv * 129X1/SvJ * CD-1 		no abnormal phenotype detected J:47966
Tfebtm1a(EUCOMM)Wtsi/Tfeb+
C57BL/6N-Tfebtm1a(EUCOMM)Wtsi/Bay 		decreased circulating alkaline phosphatase level J:211773
decreased hemoglobin content J:211773
increased lean body mass J:211773
Tfebtm1b(EUCOMM)Wtsi/Tfeb+
C57BL/6N-Tfebtm1b(EUCOMM)Wtsi/Bay 		decreased lean body mass J:211773
increased total body fat amount J:211773
trunk curl J:211773
unresponsive to tactile stimuli J:211773
Tfebtm1b(EUCOMM)Wtsi/Tfebtm1b(EUCOMM)Wtsi
C57BL/6N-Tfebtm1b(EUCOMM)Wtsi/Bay 		embryonic lethality prior to tooth bud stage J:211773
preweaning lethality, complete penetrance J:211773
Tfebtm1Est/Tfebtm1Est
involves: 129S1/Sv 		abnormal placenta morphology J:89821
prenatal lethality J:89821
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory