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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Vav2
vav 2 oncogene
MGI:102718
37 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Vav2tm1Kdf/Vav2tm1Kdf
B6.129S1-Vav2tm1Kdf
abnormal iridocorneal angle J:158008
anterior iris synechia J:158008
ocular hypertension J:158008
Vav2tm1Kdf/Vav2tm1Kdf
involves: 129S1/Sv * C57BL/6
decreased B cell proliferation J:69806
decreased IgG3 level J:69806
decreased mature B cell number J:69806
Vav2tm1Tnr/Vav2tm1Tnr
involves: 129P2/OlaHsd
abnormal adrenal gland secretion J:124056
abnormal aorta tunica media morphology J:124056
abnormal bradykinin level J:124056
abnormal class switch recombination J:69807
abnormal heart morphology J:124056
abnormal physiological response to xenobiotic J:124056
adrenal medulla hyperplasia J:124056
cardiac fibrosis J:124056
decreased B cell number J:69807
decreased B cell proliferation J:69807
decreased creatinine clearance J:124056
decreased IgG1 level J:69807
decreased IgG2b level J:69807
decreased IgG3 level J:69807
decreased IgM level J:69807
decreased spleen germinal center number J:69807
decreased urine sodium level J:124056
enlarged adrenal medulla J:124056
enlarged myocardial fiber J:124056
heart left ventricle hypertrophy J:124056
hydrocephaly J:124056
hypertension J:124056
increased circulating adrenaline level J:124056
increased circulating aldosterone level J:124056
increased circulating antidiuretic hormone level J:124056
increased circulating noradrenaline level J:124056
increased circulating renin level J:124056
increased heart rate J:124056
increased mean systemic arterial blood pressure J:124056
increased renin activity J:124056
oliguria J:124056
renal fibrosis J:124056
vascular smooth muscle hyperplasia J:124056

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory