Tcf12 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tcf12
transcription factor 12
MGI:101877

28 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Tcf12^tm1Zhu/Tcf12⁺ Tcf3^tm1Wein/Tcf3⁺ involves: 129S4/SvJaeSor	decreased pro-B cell number	J:43324
	postnatal growth retardation	J:43324
	postnatal lethality, incomplete penetrance	J:43324
Tcf12^tm1Zhu/Tcf12⁺ Tcf3^tm4Zhu/Tcf3^tm4Zhu Tg(Lck-cre)#Zhu/0 involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * SJL	abnormal T cell differentiation	J:75746
	increased double-negative T cell number	J:75746
	increased single-positive T cell number	J:75746
Tcf12^tm1Zhu/Tcf12⁺ Tcf4^tm1Zhu/Tcf4⁺ involves: 129P2/OlaHsd * 129S7/SvEvBrd	decreased pro-B cell number	J:43324
	normal nervous system phenotype	J:125313
	postnatal growth retardation	J:43324
	postnatal lethality, complete penetrance	J:43324
Tcf12^tm1Zhu/Tcf12^tm2Zhu involves: 129S7/SvEvBrd	arrested T cell differentiation	J:120411
Tcf12^tm2Zhu/Tcf12⁺ Not Specified	normal hematopoietic system phenotype	J:120411
Tcf12^tm2Zhu/Tcf12⁺ Not Specified	seizures	J:120411
Tcf12^tm2Zhu/Tcf12^tm2Zhu Not Specified	abnormal B cell differentiation	J:120411
	abnormal response to transplant	J:120411
	abnormal T cell differentiation	J:120411
	absent T cells	J:120411
	arrested T cell differentiation	J:120411
	decreased double-positive T cell number	J:120411
	decreased immature B cell number	J:120411
	decreased pre-B cell number	J:120411
	decreased pro-B cell number	J:120411
	decreased thymocyte number	J:120411
	exencephaly	J:120411
	increased double-negative T cell number	J:120411
	postnatal growth retardation	J:120411
	postnatal lethality, incomplete penetrance	J:120411
	thymus hypoplasia	J:120411
Tcf12^tm2Zhu/Tcf12^tm2Zhu Tg(TcrAND)53Hed/0 involves: C57BL/6 * SJL	abnormal CD4-positive, alpha beta T cell morphology	J:120411
	abnormal T cell subpopulation ratio	J:120411
	arrested T cell differentiation	J:120411
	increased T cell number	J:120411
Tcf12^tm3Zhu/Tcf12^tm3Zhu Tcf3^tm4Zhu/Tcf3^tm4Zhu Tg(Cd4-cre)1Cwi/0 involves: 129S4/SvJae * C57BL/6 * DBA/2	abnormal CD8-positive, alpha beta T cell morphology	J:129171
	abnormal T cell differentiation	J:129171
	decreased CD4-positive, alpha-beta T cell number	J:129171
	increased CD8-positive, alpha-beta T cell number	J:129171
Tcf12^tm3Zhu/Tcf12^tm3Zhu Tcf3^tm4Zhu/Tcf3^tm4Zhu Tg(Lck-cre)#Zhu/0 involves: 129S4/SvJae * C57BL/6 * SJL/J	decreased double-positive T cell number	J:129570
	decreased T cell number	J:129570
	increased double-negative T cell number	J:129570
	increased T cell proliferation	J:129570
	thymus hypoplasia	J:129570

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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