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Ccar1 Gene Detail
Summary
  • Symbol
    Ccar1
  • Name
    cell division cycle and apoptosis regulator 1
  • Synonyms
    2610511G16Rik, 9430036H15Rik, Carp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914750
    NCBI Gene: 67500
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:62579707-62628065 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 32.47 cM, cytoband B4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    149 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914750
protein coding gene Chr10:62579707-62628147 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017305
protein coding gene Chr10:62202733-62254208 (-)
A/J MGP_AJ_G0017283
protein coding gene Chr10:60287560-60339588 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0017243
protein coding gene Chr10:60377880-60427868 (-)
C3H/HeJ MGP_C3HHeJ_G0017066
protein coding gene Chr10:61781338-61834001 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017701
protein coding gene Chr10:64431429-64484218 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015391
protein coding gene Chr10:57242272-57291252 (-)
CAST/EiJ MGP_CASTEiJ_G0016637
protein coding gene Chr10:61832593-61887786 (-)
CBA/J MGP_CBAJ_G0017038
protein coding gene Chr10:66855322-66938570 (-)
DBA/2J MGP_DBA2J_G0017143
protein coding gene Chr10:59561944-59611345 (-)
FVB/NJ MGP_FVBNJ_G0017137
protein coding gene Chr10:58824638-58877961 (-)
LP/J MGP_LPJ_G0017217
protein coding gene Chr10:62586214-62637966 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017165
protein coding gene Chr10:69048469-69104861 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017739
protein coding gene Chr10:61709103-61762937 (-)
PWK/PhJ MGP_PWKPhJ_G0016420
protein coding gene Chr10:59433240-59483670 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016202
protein coding gene Chr10:61058048-61111062 (-)
WSB/EiJ MGP_WSBEiJ_G0016701
protein coding gene Chr10:61648347-61700766 (-)



Homology
more
  • Human Ortholog
    CCAR1, cell division cycle and apoptosis regulator 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCAR1, cell division cycle and apoptosis regulator 1
  • Links
    NCBI Gene ID: 55749
    neXtProt AC: NX_Q8IX12
    UniProt: Q8IX12

  • Chr Location
    10q21.3; chr10:68721012-68792377 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020074 Ensembl Gene Model | MGI Sequence Detail 48359 C57BL/6J ±  kb
transcript ENSMUST00000219527 Ensembl | MGI Sequence Detail 3862 Not Applicable  
polypeptide ENSMUSP00000151895 Ensembl | MGI Sequence Detail 1146 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    cDNA 21
    Primer pair 2

    Microarray probesets 7
Other
Accession IDs
less
MGI:1924537
References
more
  • Summaries
    All 50
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 15
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:302708 Liu HB, et al., RNA-Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator in Early Zygotic Genome Activation. Adv Sci (Weinh). 2019 Aug 7;6(15):1900295

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory