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Rabep1 Gene Detail
Summary
  • Symbol
    Rabep1
  • Name
    rabaptin, RAB GTPase binding effector protein 1
  • Synonyms
    neurocrescin, RAB5 effector protein, rabaptin-5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860236
    NCBI Gene: 54189
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:70735604-70833931 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 43.21 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    585 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860236
 protein coding gene Chr11:70735553-70833931 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018617
 protein coding gene Chr11:71413556-71517343 (+)
A/J MGP_AJ_G0018585
 protein coding gene Chr11:68701300-68799363 (+)
AKR/J MGP_AKRJ_G0018554
 protein coding gene Chr11:70769627-70871987 (+)
BALB/cJ MGP_BALBcJ_G0018557
 protein coding gene Chr11:69011000-69109651 (+)
C3H/HeJ MGP_C3HHeJ_G0018370
 protein coding gene Chr11:70790815-70901714 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019008
 protein coding gene Chr11:73578469-73687030 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016653
 protein coding gene Chr11:65608892-65705021 (+)
CAST/EiJ MGP_CASTEiJ_G0017925
 protein coding gene Chr11:71072834-71176812 (+)
CBA/J MGP_CBAJ_G0018342
 protein coding gene Chr11:76894752-77007529 (+)
DBA/2J MGP_DBA2J_G0018452
 protein coding gene Chr11:68277562-68378795 (+)
FVB/NJ MGP_FVBNJ_G0018442
 protein coding gene Chr11:67921404-68022642 (+)
LP/J MGP_LPJ_G0018522
 protein coding gene Chr11:71988398-72097451 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018465
 protein coding gene Chr11:77435283-77544152 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019050
 protein coding gene Chr11:71026576-71130785 (+)
PWK/PhJ MGP_PWKPhJ_G0017699
 protein coding gene Chr11:68919719-69029965 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017489
 protein coding gene Chr11:70837582-70942729 (+)
WSB/EiJ MGP_WSBEiJ_G0017979
 protein coding gene Chr11:70690016-70795110 (+)



Homology
more
  • Human Ortholog
    RABEP1, rabaptin, RAB GTPase binding effector protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RABEP1, rabaptin, RAB GTPase binding effector protein 1
  • Synonyms
    RAB5EP, RABPT5
  • Links
    NCBI Gene ID: 9135
    neXtProt AC: NX_Q15276
    UniProt: Q15276

  • Chr Location
    17p13.2; chr17:5282265-5386340 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    722
  • Tissues
    8
  • cDNA Data
    135
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020817 Ensembl Gene Model | MGI Sequence Detail 98328 C57BL/6J ±  kb
transcript ENSMUST00000108533 Ensembl | MGI Sequence Detail 2791 Not Applicable  
polypeptide ENSMUSP00000104173 Ensembl | MGI Sequence Detail 864 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 140
    Genomic 3
    cDNA 135
    Primer pair 2

    Microarray probesets 7
Other
Accession IDs
less
MGI:2144002, MGI:2144196, MGI:2144463, MGI:2144517
References
more
  • Summaries
    All 65
    Developmental Gene Expression 4
    Gene Ontology 12
    Phenotypes 18
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:267911 Timmermans S, et al., Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J. JCI Insight. 2018 Jul 12;3(13)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory