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Ip6k1
Gene Detail
 Symbol
Name
ID
Ip6k1
inositol hexaphosphate kinase 1
MGI:1351633
Synonyms 1200016D08Rik, Ihpk1, InsP6
Feature Type protein coding gene
Genetic Map
Chromosome 9
59.07 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:108002501-108048780 bp, + strand
From VEGA annotation of GRCm38

  46280 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:56602  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Ip6k1
Human
homologs
Human Homolog IP6K1, inositol hexakisphosphate kinase 1
NCBI Gene ID 9807
neXtProt AC  NX_Q92551
Human Synonyms  IHPK1, PiUS
Human Chr (Location)  3p21.31; chr3:49761728-49823973 (-)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(3) : Targeted(2) Gene trapped(1)
 
Homozygous mutation of this gene results in impaired glucose tolerance, decreased insulin levels, bilateral epididymal aspermia, and testicular degeneration in males.
 
Phenotype Images(1)
Gene Ontology
(GO)
classifications 		All GO classifications: (16 annotations)
Process inositol metabolic process, inositol phosphate biosynthetic process, ...
Component cytoplasm, nucleolus, ...
Function ATP binding, inositol-1,4,5-trisphosphate 3-kinase activity, ...
External Resources: FuncBase
Expression Literature Summary: (2 records)
Data Summary: Results (102)    Tissues (97)    Images (16)
Theiler Stages: 22
Assay TypeResults
RNA in situ 102
cDNA source data(217)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(217) cDNA(217)
Microarray probesets(8)
Other database
links
VEGA Gene ModelOTTMUSG00000042012 (Evidence)
Ensembl Gene ModelENSMUSG00000032594 (Evidence)
Entrez Gene27399 (Evidence)
UniGene276155
DFCITC1609875, TC1655812, TC1742934
DoTSDT.101142237, DT.110616421, DT.110616487, DT.535470, DT.91365501, DT.91446469, DT.94233218, DT.94233238, DT.97396692
EC2.7.4.21
Consensus CDS ProjectCCDS23514.1
International Mouse Knockout Project StatusIp6k1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042012 VEGA Gene Model | MGI Sequence Detail 46280 C57BL/6J ±  kb
transcript OTTMUST00000110103 VEGA | MGI Sequence Detail 4557 Not Applicable 
polypeptide OTTMUSP00000061354 VEGA | MGI Sequence Detail 433 Not Applicable 

For the selected sequences
All sequences(114) RefSeq(2) UniProt(8)
Polymorphisms SNPs(83 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR005522 Inositol polyphosphate kinase
Protein Ontology PR:000009080 inositol hexakisphosphate kinase 1
References (Earliest) J:58528 Saiardi A, et al., Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases. Curr Biol. 1999 Nov 18;9(22):1323-6
(Latest) J:177831 Szijgyarto Z, et al., Influence of inositol pyrophosphates on cellular energy dynamics. Science. 2011 Nov 11;334(6057):802-5
All references(39)
Other
accession IDs 		MGI:1914851, MGI:2143219
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory