GO Annotations Graph

• Symbol: Lhx1
• Name: LIM homeobox protein 1
• ID: MGI:99783

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:226614
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IMP	J:104938
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IMP	J:166792
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IMP	J:74124
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IMP	J:172979
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IGI	J:117030
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TAS	J:226614
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:118838
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005622	intracellular anatomical structure	IDA	J:57340
Cellular Component	GO:0005634	nucleus	IDA	J:130904
Cellular Component	GO:0005634	nucleus	IDA	J:105233
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:60703
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:130846
Cellular Component	GO:0032991	protein-containing complex	IDA	J:98485
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:226614
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	IMP	J:98831
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	IGI	J:53656
Biological Process	GO:0009653	anatomical structure morphogenesis	IMP	J:226614
Biological Process	GO:0009653	anatomical structure morphogenesis	IMP	J:98831
Biological Process	GO:0009653	anatomical structure morphogenesis	IMP	J:55061
Biological Process	GO:0009948	anterior/posterior axis specification	IGI	J:41878
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:53656
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IEP	J:173750
Biological Process	GO:0030154	cell differentiation	IMP	J:226614
Biological Process	GO:0007267	cell-cell signaling	IGI	J:123471
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	IGI	J:123471
Biological Process	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	IGI	J:123471
Biological Process	GO:0021549	cerebellum development	IGI	J:123471
Biological Process	GO:0060067	cervix development	IMP	J:133086
Biological Process	GO:0072049	comma-shaped body morphogenesis	IMP	J:172979
Biological Process	GO:0009953	dorsal/ventral pattern formation	IGI	J:53656
Biological Process	GO:0001705	ectoderm formation	IGI	J:53656
Biological Process	GO:0009880	embryonic pattern specification	IGI	J:41878
Biological Process	GO:0060059	embryonic retina morphogenesis in camera-type eye	IMP	J:130904
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	IMP	J:133086
Biological Process	GO:0007492	endoderm development	IMP	J:226614
Biological Process	GO:0001706	endoderm formation	IMP	J:93592
Biological Process	GO:0060429	epithelium development	IMP	J:133086
Biological Process	GO:0021871	forebrain regionalization	IGI	J:41878
Biological Process	GO:0001702	gastrulation with mouth forming second	IMP	J:93592
Biological Process	GO:0060322	head development	IGI	J:98485
Biological Process	GO:0060322	head development	IGI	J:41878
Biological Process	GO:0001822	kidney development	IMP	J:98831
Biological Process	GO:0097477	lateral motor column neuron migration	IMP	J:166792
Biological Process	GO:0048382	mesendoderm development	IMP	J:226614
Biological Process	GO:0001823	mesonephros development	IEP	J:173750
Biological Process	GO:0072283	metanephric renal vesicle morphogenesis	IEP	J:173750
Biological Process	GO:0072284	metanephric S-shaped body morphogenesis	IEP	J:173750
Biological Process	GO:0001656	metanephros development	IEP	J:173750
Biological Process	GO:0008045	motor neuron axon guidance	IMP	J:166792
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:172979
Biological Process	GO:0035849	nephric duct elongation	IMP	J:104938
Biological Process	GO:0072178	nephric duct morphogenesis	IMP	J:104938
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0030182	neuron differentiation	IBA	J:265628
Biological Process	GO:0060066	oviduct development	IMP	J:133086
Biological Process	GO:0035846	oviduct epithelium development	IMP	J:133086
Biological Process	GO:0061205	paramesonephric duct development	IMP	J:133086
Biological Process	GO:0007389	pattern specification process	IMP	J:98831
Biological Process	GO:0007389	pattern specification process	IGI	J:53656
Biological Process	GO:2000744	positive regulation of anterior head development	IMP	J:133086
Biological Process	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	IMP	J:104938
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:166792
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IGI	J:117030
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:172979
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:104938
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:74124
Biological Process	GO:0040019	positive regulation of embryonic development	IMP	J:74124
Biological Process	GO:2000543	positive regulation of gastrulation	IMP	J:74124
Biological Process	GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	IMP	J:104938
Biological Process	GO:0009791	post-embryonic development	IMP	J:123471
Biological Process	GO:0090009	primitive streak formation	IMP	J:74124
Biological Process	GO:0090009	primitive streak formation	IMP	J:74124
Biological Process	GO:0048793	pronephros development	IEP	J:173750
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0010468	regulation of gene expression	IMP	J:55061
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0072077	renal vesicle morphogenesis	IMP	J:172979
Biological Process	GO:0060041	retina development in camera-type eye	IEP	J:60703
Biological Process	GO:0010842	retina layer formation	IMP	J:130904
Biological Process	GO:0010842	retina layer formation	IEP	J:60703
Biological Process	GO:0072050	S-shaped body morphogenesis	IMP	J:172979
Biological Process	GO:0032525	somite rostral/caudal axis specification	IMP	J:74124
Biological Process	GO:0032525	somite rostral/caudal axis specification	IMP	J:74124
Biological Process	GO:0021527	spinal cord association neuron differentiation	IGI	J:117030
Biological Process	GO:0021510	spinal cord development	IEP	J:173750
Biological Process	GO:0021537	telencephalon development	IEP	J:173750
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:98485
Biological Process	GO:0072197	ureter morphogenesis	IGI	J:174353
Biological Process	GO:0072197	ureter morphogenesis	IGI	J:174353
Biological Process	GO:0072197	ureter morphogenesis	IGI	J:174353
Biological Process	GO:0072197	ureter morphogenesis	IGI	J:174353
Biological Process	GO:0001657	ureteric bud development	IMP	J:98831
Biological Process	GO:0001655	urogenital system development	IMP	J:98831
Biological Process	GO:0035847	uterine epithelium development	IMP	J:133086
Biological Process	GO:0060065	uterus development	IMP	J:133086
Biological Process	GO:0060068	vagina development	IMP	J:133086
Biological Process	GO:0021517	ventral spinal cord development	IEP	J:166792