GO Annotations Graph

• Symbol: Epha5
• Name: Eph receptor A5
• ID: MGI:99654

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005003	ephrin receptor activity	ISO	J:155856
Molecular Function	GO:0005004	GPI-linked ephrin receptor activity	IDA	J:177156
Molecular Function	GO:0019838	growth factor binding	ISO	J:155856
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:180801
Molecular Function	GO:0005515	protein binding	IPI	J:51889
Molecular Function	GO:0005515	protein binding	IPI	J:51889
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004713	protein tyrosine kinase activity	IEA	J:72247
Molecular Function	GO:0004713	protein tyrosine kinase activity	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IBA	J:265628
Cellular Component	GO:0005912	adherens junction	IDA	J:194293
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0071944	cell periphery	IDA	J:194293
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0030425	dendrite	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Cellular Component	GO:0005791	rough endoplasmic reticulum	ISO	J:164563
Biological Process	GO:0001525	angiogenesis	IBA	J:265628
Biological Process	GO:0007411	axon guidance	IDA	J:78359
Biological Process	GO:0019933	cAMP-mediated signaling	ISO	J:155856
Biological Process	GO:0071372	cellular response to follicle-stimulating hormone stimulus	IDA	J:194293
Biological Process	GO:1904322	cellular response to forskolin	IDA	J:194293
Biological Process	GO:0060997	dendritic spine morphogenesis	ISO	J:155856
Biological Process	GO:0048013	ephrin receptor signaling pathway	IDA	J:177156
Biological Process	GO:0048013	ephrin receptor signaling pathway	ISO	J:155856
Biological Process	GO:0048013	ephrin receptor signaling pathway	IBA	J:265628
Biological Process	GO:0021766	hippocampus development	IDA	J:78359
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0007162	negative regulation of cell adhesion	ISO	J:194293
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0032793	positive regulation of CREB transcription factor activity	ISO	J:155856
Biological Process	GO:0033674	positive regulation of kinase activity	IBA	J:265628
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	IDA	J:177156
Biological Process	GO:0043087	regulation of GTPase activity	IDA	J:177156
Biological Process	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	IDA	J:177156
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IEA	J:72247