Wnt1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Wnt1
wingless-type MMTV integration site family, member 1
MGI:98953

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	IDA	J:161039
Molecular Function	GO:0005125	cytokine activity	IBA	J:265628
Molecular Function	GO:0005109	frizzled binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:154679
Molecular Function	GO:0005515	protein binding	IPI	J:204648
Molecular Function	GO:0005515	protein binding	IPI	J:123536
Molecular Function	GO:0005515	protein binding	IPI	J:154679
Molecular Function	GO:0005515	protein binding	IPI	J:162153
Molecular Function	GO:0005515	protein binding	IPI	J:166033
Molecular Function	GO:0005515	protein binding	IPI	J:101423
Molecular Function	GO:0005515	protein binding	IPI	J:63226
Molecular Function	GO:0005515	protein binding	IPI	J:75973
Molecular Function	GO:0005515	protein binding	IPI	J:93897
Molecular Function	GO:0019904	protein domain specific binding	IPI	J:93897
Molecular Function	GO:0048018	receptor ligand activity	IDA	J:161039
Molecular Function	GO:0048018	receptor ligand activity	ISO	J:164563
Molecular Function	GO:0048018	receptor ligand activity	IC	J:231273
Molecular Function	GO:0005102	signaling receptor binding	TAS	J:52010
Cellular Component	GO:0009986	cell surface	IDA	J:34493
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005788	endoplasmic reticulum lumen	TAS	Reactome:R-MMU-3238692
Cellular Component	GO:0005576	extracellular region	IDA	J:162153
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:1990909	Wnt signalosome	IC	J:161039
Biological Process	GO:0009887	animal organ morphogenesis	TAS	J:52010
Biological Process	GO:0031100	animal organ regeneration	ISO	J:155856
Biological Process	GO:0036520	astrocyte-dopaminergic neuron signaling	IMP	J:231273
Biological Process	GO:0030509	BMP signaling pathway	ISO	J:157031
Biological Process	GO:0060348	bone development	ISO	J:164563
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IGI	J:100575
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:225408
Biological Process	GO:0060070	canonical Wnt signaling pathway	NAS	J:91004
Biological Process	GO:0060070	canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:231273
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:164788
Biological Process	GO:0060070	canonical Wnt signaling pathway	TAS	J:225650
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:172892
Biological Process	GO:0060070	canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:106811
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:125420
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:91019
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:113117
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:48026
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:160170
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:95052
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:90938
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:67003
Biological Process	GO:1904954	canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	IDA	J:228113
Biological Process	GO:0045165	cell fate commitment	IBA	J:265628
Biological Process	GO:0008283	cell population proliferation	IDA	J:40358
Biological Process	GO:0033278	cell proliferation in midbrain	IDA	J:86401
Biological Process	GO:0033278	cell proliferation in midbrain	IDA	J:91004
Biological Process	GO:0007267	cell-cell signaling	IDA	J:161039
Biological Process	GO:0007267	cell-cell signaling	TAS	J:52010
Biological Process	GO:0021551	central nervous system morphogenesis	IMP	J:67737
Biological Process	GO:0021549	cerebellum development	IMP	J:35491
Biological Process	GO:0021588	cerebellum formation	IMP	J:67737
Biological Process	GO:0021536	diencephalon development	IGI	J:130851
Biological Process	GO:0071542	dopaminergic neuron differentiation	TAS	J:227390
Biological Process	GO:0071542	dopaminergic neuron differentiation	IMP	J:193686
Biological Process	GO:0000578	embryonic axis specification	IMP	J:163659
Biological Process	GO:1990403	embryonic brain development	IDA	J:91004
Biological Process	GO:0045444	fat cell differentiation	IDA	J:97016
Biological Process	GO:0021797	forebrain anterior/posterior pattern specification	IGI	J:130851
Biological Process	GO:0071425	hematopoietic stem cell proliferation	IDA	J:40358
Biological Process	GO:0071425	hematopoietic stem cell proliferation	IDA	J:40358
Biological Process	GO:0070365	hepatocyte differentiation	ISO	J:155856
Biological Process	GO:0042472	inner ear morphogenesis	IGI	J:99408
Biological Process	GO:0022037	metencephalon development	IMP	J:10730
Biological Process	GO:0030901	midbrain development	IDA	J:86401
Biological Process	GO:0030901	midbrain development	IMP	J:35491
Biological Process	GO:0030901	midbrain development	IMP	J:67737
Biological Process	GO:0030901	midbrain development	IMP	J:10730
Biological Process	GO:1904948	midbrain dopaminergic neuron differentiation	IMP	J:193686
Biological Process	GO:0030917	midbrain-hindbrain boundary development	IMP	J:10730
Biological Process	GO:0030917	midbrain-hindbrain boundary development	IMP	J:10730
Biological Process	GO:0022004	midbrain-hindbrain boundary maturation during brain development	IMP	J:29060
Biological Process	GO:0022004	midbrain-hindbrain boundary maturation during brain development	IMP	J:29060
Biological Process	GO:0007275	multicellular organism development	IEA	J:72247
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007520	myoblast fusion	IDA	J:95052
Biological Process	GO:0007520	myoblast fusion	IGI	J:95052
Biological Process	GO:0014902	myotube differentiation	IGI	J:95052
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	ISO	J:164563
Biological Process	GO:0045596	negative regulation of cell differentiation	IMP	J:196129
Biological Process	GO:0022408	negative regulation of cell-cell adhesion	ISO	J:164563
Biological Process	GO:0010812	negative regulation of cell-substrate adhesion	ISO	J:164563
Biological Process	GO:2000773	negative regulation of cellular senescence	ISO	J:164563
Biological Process	GO:0045599	negative regulation of fat cell differentiation	IMP	J:125420
Biological Process	GO:0045599	negative regulation of fat cell differentiation	IDA	J:125420
Biological Process	GO:0045599	negative regulation of fat cell differentiation	IDA	J:97016
Biological Process	GO:1903204	negative regulation of oxidative stress-induced neuron death	IMP	J:231273
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	IDA	J:109361
Biological Process	GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	IDA	J:109361
Biological Process	GO:0022008	neurogenesis	IDA	J:86401
Biological Process	GO:0030182	neuron differentiation	IBA	J:265628
Biological Process	GO:0048663	neuron fate commitment	IMP	J:104370
Biological Process	GO:0048664	neuron fate determination	IMP	J:104370
Biological Process	GO:0008284	positive regulation of cell population proliferation	TAS	J:225650
Biological Process	GO:0008284	positive regulation of cell population proliferation	TAS	J:225650
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0061184	positive regulation of dermatome development	ISO	J:164563
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	IDA	J:107732
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:159074
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:44227
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	ISO	J:164563
Biological Process	GO:1902035	positive regulation of hematopoietic stem cell proliferation	IDA	J:40358
Biological Process	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	ISO	J:164563
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IDA	J:91019
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NAS	J:35491
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:228113
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:94453
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:94453
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:94453
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:50462
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:94453
Biological Process	GO:0006355	regulation of DNA-templated transcription	TAS	J:225650
Biological Process	GO:0007165	signal transduction	TAS	J:52010
Biological Process	GO:0042770	signal transduction in response to DNA damage	ISO	J:164563
Biological Process	GO:0060061	Spemann organizer formation	IMP	J:41504
Biological Process	GO:0021527	spinal cord association neuron differentiation	IGI	J:75367
Biological Process	GO:0033077	T cell differentiation in thymus	IDA	J:67003
Biological Process	GO:0030579	ubiquitin-dependent SMAD protein catabolic process	IDA	J:109361
Biological Process	GO:0016055	Wnt signaling pathway	IDA	J:227398

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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