GO Annotations Graph

• Symbol: Rxrb
• Name: retinoid X receptor beta
• ID: MGI:98215

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:264834
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:155856
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:164563
Molecular Function	GO:0004879	nuclear receptor activity	IBA	J:265628
Molecular Function	GO:0030374	nuclear receptor coactivator activity	ISO	J:155856
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	ISO	J:155856
Molecular Function	GO:0003707	nuclear steroid receptor activity	IEA	J:72247
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	ISO	J:155856
Molecular Function	GO:0042809	nuclear vitamin D receptor binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:113776
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0044323	retinoic acid-responsive element binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IGI	J:22384
Molecular Function	GO:0043565	sequence-specific DNA binding	IGI	J:22384
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:162985
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IBA	J:265628
Biological Process	GO:0048856	anatomical structure development	IBA	J:265628
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:44836
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0071300	cellular response to retinoic acid	IDA	J:162985
Biological Process	GO:0001701	in utero embryonic development	IGI	J:52278
Biological Process	GO:0001893	maternal placenta development	IGI	J:52278
Biological Process	GO:0030501	positive regulation of bone mineralization	NAS	J:319681
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:22384
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:22384
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0031641	regulation of myelination	ISO	J:155856
Biological Process	GO:0032526	response to retinoic acid	IBA	J:265628
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	IBA	J:265628
Biological Process	GO:0055012	ventricular cardiac muscle cell differentiation	IMP	J:44836
Biological Process	GO:0055012	ventricular cardiac muscle cell differentiation	IGI	J:44836