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GO Annotations Graph
Symbol
Name
ID
Pax8
paired box 8
MGI:97492

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0003677DNA bindingISOJ:164563
Molecular FunctionGO:0003677DNA bindingISOJ:155856
Molecular FunctionGO:0003677DNA bindingISSJ:35102
Molecular FunctionGO:0005515protein bindingIPIJ:116251
Molecular FunctionGO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA bindingISOJ:155856
Molecular FunctionGO:0000979RNA polymerase II core promoter sequence-specific DNA bindingISOJ:164563
Molecular FunctionGO:0043565sequence-specific DNA bindingISOJ:155856
Molecular FunctionGO:0003700transcription factor activity, sequence-specific DNA bindingTASJ:54357
Molecular FunctionGO:0003700transcription factor activity, sequence-specific DNA bindingISOJ:164563
Molecular FunctionGO:0044212transcription regulatory region DNA bindingIDAJ:117753
Molecular FunctionGO:0044212transcription regulatory region DNA bindingISOJ:164563
Molecular FunctionGO:0001077transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingISOJ:155856
Cellular ComponentGO:0005654nucleoplasmISOJ:155856
Cellular ComponentGO:0005654nucleoplasmISOJ:164563
Cellular ComponentGO:0005634nucleusISOJ:155856
Cellular ComponentGO:0005634nucleusIDAJ:144755
Cellular ComponentGO:0005634nucleusISOJ:164563
Cellular ComponentGO:0005667transcription factor complexTASJ:54357
Biological ProcessGO:0030154cell differentiationIMPJ:47310
Biological ProcessGO:0071371cellular response to gonadotropin stimulusISOJ:164563
Biological ProcessGO:0042472inner ear morphogenesisIGIJ:163537
Biological ProcessGO:0001823mesonephros developmentIMPJ:80208
Biological ProcessGO:0072221metanephric distal convoluted tubule developmentIMPJ:120229
Biological ProcessGO:0072289metanephric nephron tubule formationIMPJ:120229
Biological ProcessGO:0001656metanephros developmentIGIJ:80208
Biological ProcessGO:0007275multicellular organism developmentIEAJ:60000
Biological ProcessGO:1900215negative regulation of apoptotic process involved in metanephric collecting duct developmentIMPJ:120229
Biological ProcessGO:1900218negative regulation of apoptotic process involved in metanephric nephron tubule developmentIMPJ:120229
Biological ProcessGO:0072305negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesisIMPJ:120229
Biological ProcessGO:1900212negative regulation of mesenchymal cell apoptotic process involved in metanephros developmentIMPJ:120229
Biological ProcessGO:0009887organ morphogenesisTASJ:54357
Biological ProcessGO:0090190positive regulation of branching involved in ureteric bud morphogenesisIMPJ:120229
Biological ProcessGO:0072108positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisIMPJ:80208
Biological ProcessGO:2000594positive regulation of metanephric DCT cell differentiationIMPJ:120229
Biological ProcessGO:2000611positive regulation of thyroid hormone generationISOJ:164563
Biological ProcessGO:2000611positive regulation of thyroid hormone generationIMPJ:115535
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:41061
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:155856
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIMPJ:115535
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIDAJ:116251
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIDAJ:117753
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIMPJ:120229
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedISOJ:164563
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIGIJ:104408
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIMPJ:80208
Biological ProcessGO:0048793pronephros developmentIMPJ:80208
Biological ProcessGO:0042981regulation of apoptotic processIMPJ:80208
Biological ProcessGO:0072307regulation of metanephric nephron tubule epithelial cell differentiationIMPJ:120229
Biological ProcessGO:2000612regulation of thyroid-stimulating hormone secretionISOJ:164563
Biological ProcessGO:0006355regulation of transcription, DNA-templatedISOJ:155856
Biological ProcessGO:0006355regulation of transcription, DNA-templatedTASJ:54357
Biological ProcessGO:0030878thyroid gland developmentISOJ:164563
Biological ProcessGO:0030878thyroid gland developmentIGIJ:73626
Biological ProcessGO:0030878thyroid gland developmentIMPJ:47310
Biological ProcessGO:0006366transcription from RNA polymerase II promoterISOJ:155856
Biological ProcessGO:0006351transcription, DNA-templatedISOJ:164563
Biological ProcessGO:0006351transcription, DNA-templatedIDAJ:31258
Biological ProcessGO:0001655urogenital system developmentIGIJ:80208


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory