GO Annotations Graph

• Symbol: Pax3
• Name: paired box 3
• ID: MGI:97487

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:96431
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TAS	J:54357
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IGI	J:96431
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:96431
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IGI	J:96431
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IGI	J:96431
Molecular Function	GO:0071837	HMG box domain binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:127196
Molecular Function	GO:0005515	protein binding	IPI	J:45398
Molecular Function	GO:0005515	protein binding	IPI	J:96431
Molecular Function	GO:0005515	protein binding	IPI	J:103937
Molecular Function	GO:0005515	protein binding	IPI	J:189874
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:75158
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:75158
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0001221	transcription coregulator binding	IPI	J:289456
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:170376
Cellular Component	GO:0005667	transcription regulator complex	TAS	J:54357
Biological Process	GO:0048856	anatomical structure development	IBA	J:265628
Biological Process	GO:0055007	cardiac muscle cell differentiation	NAS	J:173154
Biological Process	GO:0016477	cell migration	IMP	J:142168
Biological Process	GO:0008283	cell population proliferation	IMP	J:102820
Biological Process	GO:0048066	developmental pigmentation	IMP	J:92947
Biological Process	GO:0007507	heart development	IMP	J:96055
Biological Process	GO:0060594	mammary gland specification	IMP	J:109476
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007517	muscle organ development	IMP	J:90568
Biological Process	GO:0007517	muscle organ development	IMP	J:90568
Biological Process	GO:0007517	muscle organ development	IMP	J:90568
Biological Process	GO:0007517	muscle organ development	IMP	J:90568
Biological Process	GO:0051451	myoblast migration	IMP	J:90568
Biological Process	GO:0051451	myoblast migration	IMP	J:90568
Biological Process	GO:0051451	myoblast migration	IMP	J:90568
Biological Process	GO:0051451	myoblast migration	IMP	J:90568
Biological Process	GO:0051450	myoblast proliferation	IMP	J:90568
Biological Process	GO:0051450	myoblast proliferation	IMP	J:90568
Biological Process	GO:0051450	myoblast proliferation	IMP	J:90568
Biological Process	GO:0051450	myoblast proliferation	IMP	J:90568
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:96431
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:96431
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0001755	neural crest cell migration	IMP	J:93195
Biological Process	GO:0001843	neural tube closure	IMP	J:93195
Biological Process	GO:0021915	neural tube development	IGI	J:56680
Biological Process	GO:0048663	neuron fate commitment	IGI	J:51645
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:75158
Biological Process	GO:2000648	positive regulation of stem cell proliferation	IMP	J:102820
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:75158
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:103937
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:96431
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0014807	regulation of somitogenesis	IGI	J:142168
Biological Process	GO:0014807	regulation of somitogenesis	IMP	J:142168
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0035914	skeletal muscle cell differentiation	NAS	J:173154
Biological Process	GO:0060538	skeletal muscle organ development	IMP	J:209494
Biological Process	GO:0060538	skeletal muscle organ development	IMP	J:209494
Biological Process	GO:0021527	spinal cord association neuron differentiation	IGI	J:51645
Biological Process	GO:0072089	stem cell proliferation	IMP	J:102820