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GO Annotations Graph
Symbol
Name
ID
Flt4
FMS-like tyrosine kinase 4
MGI:95561

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0019838growth factor bindingISOJ:155856
Molecular FunctionGO:0019838growth factor bindingISOJ:164563
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:200377
Molecular FunctionGO:0005515protein bindingIPIJ:159519
Molecular FunctionGO:0005515protein bindingIPIJ:46616
Molecular FunctionGO:0005515protein bindingIPIJ:69764
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0019903protein phosphatase bindingISOJ:164563
Molecular FunctionGO:0004713protein tyrosine kinase activityIEAJ:72247
Molecular FunctionGO:0004713protein tyrosine kinase activityIEAJ:60000
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Molecular FunctionGO:0004714transmembrane receptor protein tyrosine kinase activityISOJ:164563
Molecular FunctionGO:0005021vascular endothelial growth factor-activated receptor activityISOJ:155856
Molecular FunctionGO:0005021vascular endothelial growth factor-activated receptor activityISOJ:73065
Molecular FunctionGO:0005021vascular endothelial growth factor-activated receptor activityIGIJ:46616
Cellular ComponentGO:0005737cytoplasmIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0005887integral component of plasma membraneIEAJ:72247
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0016020membraneIEAJ:72247
Cellular ComponentGO:0005634nucleusIEAJ:60000
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Cellular ComponentGO:0043235receptor complexISOJ:194542
Biological ProcessGO:0001525angiogenesisIEAJ:60000
Biological ProcessGO:0048514blood vessel morphogenesisIMPJ:50761
Biological ProcessGO:0035924cellular response to vascular endothelial growth factor stimulusISOJ:164563
Biological ProcessGO:0048286lung alveolus developmentIMPJ:213127
Biological ProcessGO:0001945lymph vessel developmentIGIJ:159519
Biological ProcessGO:0001945lymph vessel developmentIMPJ:157791
Biological ProcessGO:0001946lymphangiogenesisIMPJ:177405
Biological ProcessGO:0001946lymphangiogenesisISOJ:164563
Biological ProcessGO:0043066negative regulation of apoptotic processISOJ:164563
Biological ProcessGO:0018108peptidyl-tyrosine phosphorylationISOJ:164563
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0030307positive regulation of cell growthISOJ:155856
Biological ProcessGO:0008284positive regulation of cell proliferationIGIJ:46616
Biological ProcessGO:0008284positive regulation of cell proliferationISOJ:73065
Biological ProcessGO:0010595positive regulation of endothelial cell migrationISOJ:164563
Biological ProcessGO:0001938positive regulation of endothelial cell proliferationISOJ:164563
Biological ProcessGO:0070374positive regulation of ERK1 and ERK2 cascadeISOJ:164563
Biological ProcessGO:0046330positive regulation of JNK cascadeISOJ:164563
Biological ProcessGO:0043410positive regulation of MAPK cascadeISOJ:164563
Biological ProcessGO:0090037positive regulation of protein kinase C signalingISOJ:164563
Biological ProcessGO:0001934positive regulation of protein phosphorylationISOJ:164563
Biological ProcessGO:0010575positive regulation of vascular endothelial growth factor productionISOJ:164563
Biological ProcessGO:0046777protein autophosphorylationISOJ:164563
Biological ProcessGO:0006468protein phosphorylationIEAJ:72247
Biological ProcessGO:0060312regulation of blood vessel remodelingIMPJ:50761
Biological ProcessGO:0007585respiratory gaseous exchangeIMPJ:213127
Biological ProcessGO:0003016respiratory system processIMPJ:213127
Biological ProcessGO:0002040sprouting angiogenesisIMPJ:138577
Biological ProcessGO:0007169transmembrane receptor protein tyrosine kinase signaling pathwayIEAJ:72247
Biological ProcessGO:0048010vascular endothelial growth factor receptor signaling pathwayISOJ:73065
Biological ProcessGO:0048010vascular endothelial growth factor receptor signaling pathwayISOJ:155856
Biological ProcessGO:0048010vascular endothelial growth factor receptor signaling pathwayISOJ:73065
Biological ProcessGO:0038084vascular endothelial growth factor signaling pathwayISOJ:164563
Biological ProcessGO:0038084vascular endothelial growth factor signaling pathwayISOJ:155856
Biological ProcessGO:0001944vasculature developmentIMPJ:50761


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/02/2021
MGI 6.16
The Jackson Laboratory